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Concordance study between the ParaDNA® Intelligence Test, a rapid DNA profiling assay, and a conventional STR typing kit (AmpFlSTR® SGM Plus®).

Ball, G and Dawnay, N and Stafford-Allen, B and Panasiuk, M and Rendell, P and Blackman, S and Duxbury, N and Wells, S (2015) Concordance study between the ParaDNA® Intelligence Test, a rapid DNA profiling assay, and a conventional STR typing kit (AmpFlSTR® SGM Plus®). Forensic Science International: Genetics, 16. pp. 48-51. ISSN 1878-0326

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Abstract

The ParaDNA® Intelligence Test enables STR profiling directly from human biological samples and evidence items collected from crime scene in 75min. Designed for non-expert use this system allows DNA information to be available to investigators before it would typically be available from a laboratory. The ParaDNA Intelligence Test system amplifies D3S1358, D8S119, D16S539, D18S1358 and TH01 STR loci and the gender typing locus amelogenin and detects the alleles present with HyBeacon® probes. Individual DNA samples from 381 UK Caucasian individuals were analysed using AmpFlSTR® SGM Plus® and the ParaDNA Intelligence Test with the derived STR profiles compared. Here we describe the high level of concordance demonstrated between the two systems and discuss this with reference to allele frequencies and the discriminatory power offered by the ParaDNA Intelligence Test.

Item Type: Article
Uncontrolled Keywords: 06 Biological Sciences, 01 Mathematical Sciences, 18 Law And Legal Studies
Subjects: Q Science > QH Natural history > QH301 Biology
R Medicine > RA Public aspects of medicine > RA1001 Forensic Medicine. Medical jurisprudence. Legal medicine
Divisions: Pharmacy & Biomolecular Sciences
Publisher: Elsevier
Related URLs:
Date Deposited: 09 Feb 2016 12:02
Last Modified: 09 Feb 2016 12:02
DOI or Identification number: 10.1016/j.fsigen.2014.12.006
URI: http://researchonline.ljmu.ac.uk/id/eprint/2884

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