Facial reconstruction

Search LJMU Research Online

Browse Repository | Browse E-Theses

Anabolic steroids detected in bodybuilding dietary supplements - a significant risk to public health

Abbate, V and Kicman, AT and Evans-Brown, M and McVeigh, J and Cowan, DA and Wilson, C and Coles, SJ and Walker, CJ (2015) Anabolic steroids detected in bodybuilding dietary supplements - a significant risk to public health. DRUG TESTING AND ANALYSIS, 7 (7). pp. 609-618. ISSN 1942-7603

Full text not available from this repository. Please see publisher link below:

Abstract

Twenty-four products suspected of containing anabolic steroids and sold in fitness equipment shops in the United Kingdom (UK) were analyzed for their qualitative and semi-quantitative content using full scan gas chromatography-mass spectrometry (GC-MS), accurate mass liquid chromatography-mass spectrometry (LC-MS), high pressure liquid chromatography with diode array detection (HPLC-DAD), UV-Vis, and nuclear magnetic resonance (NMR) spectroscopy. In addition, X-ray crystallography enabled the identification of one of the compounds, where reference standard was not available. Of the 24 products tested, 23 contained steroids including known anabolic agents; 16 of these contained steroids that were different to those indicated on the packaging and one product contained no steroid at all. Overall, 13 different steroids were identified; 12 of these are controlled in the UK under the Misuse of Drugs Act 1971. Several of the products contained steroids that may be considered to have considerable pharmacological activity, based on their chemical structures and the amounts present. This could unwittingly expose users to a significant risk to their health, which is of particular concern for naïve users.

Item Type: Article
Uncontrolled Keywords: 0301 Analytical Chemistry, 1115 Pharmacology And Pharmaceutical Sciences
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Public Health Institute
Publisher: WILEY-BLACKWELL
Related URLs:
Date Deposited: 11 May 2016 11:21
Last Modified: 11 May 2016 11:21
DOI or Identification number: 10.1002/dta.1728
URI: http://researchonline.ljmu.ac.uk/id/eprint/3592

Actions (login required)

View Item View Item