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Utility of three anthropometric indices in assessing the cardiometabolic risk profile in children

Buchan, DS and Boddy, LM and Grace, FM and Brown, E and Sculthorpe, N and Cunningham, C and Murphy, MH and Dagger, R and Foweather, L and Graves, LEF and Hopkins, ND and Stratton, G and Baker, JS (2017) Utility of three anthropometric indices in assessing the cardiometabolic risk profile in children. AMERICAN JOURNAL OF HUMAN BIOLOGY, 29 (3). ISSN 1042-0533

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Abstract

Objectives: To evaluate the ability of BMI, WC and WHtR to identify increased cardiometabolic risk in pre-adolescents.
Methods: This is a cross-sectional study involving 192 children (10.92 ± 0.58 years, 56% female) from the United Kingdom between 2010 and 2013. Receiver operating characteristic curves determined the discriminatory ability of BMI, WC and WHtR to identify individuals with increased cardiometabolic risk (increased clustered triglycerides, HDL-cholesterol, systolic blood pressure, cardiorespiratory fitness and glucose).
Results: A WHtR ≥ 0.5 increased the odds by 5.2 (95% confidence interval 2.6, 10.3) of having increased cardiometabolic risk. Similar associations were observed for BMI and WC. Both BMI-z and WHtR were fair predictors of increased cardiometabolic risk although BMI-z demonstrated the best trade-off between sensitivity and specificity, 76.1% and 63.6%, compared to 68.1% and 65.5% for WHtR. Cross-validation analysis revealed that BMI-z and WHtR correctly classified 84% of individuals (kappa score = 0.671, 95% CI 0.55, 0.79). The sensitivity of the cut-points suggests that 89.3% of individuals were correctly classified as being at risk with only 10.7% misdiagnosed whereas the specificity of the cut-points indicated that 77.8% of individuals were correctly identified as being healthy with 22.2% of individuals incorrectly diagnosed as being at risk.
Conclusions: Findings suggest that WHtR provides similar cardiometabolic risk estimates to age and sex adjusted BMI.

Item Type: Article
Additional Information: This is the accepted version of the following article: Buchan DS, Boddy LM, Grace FM, et al. Utility of three anthropometric indices in assessing the cardiometabolic risk profile in children. Am J Hum Biol. 2017;29:e22934. https://doi.org/10.1002/ajhb.22934, which has been published in final form at http://dx.doi.org/10.1002/ajhb.22934
Uncontrolled Keywords: 0603 Evolutionary Biology, 1601 Anthropology, 1111 Nutrition And Dietetics
Subjects: R Medicine > RC Internal medicine > RC1200 Sports Medicine
R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services
Divisions: Sport & Exercise Sciences
Publisher: Wiley: 12 months
Date Deposited: 11 Oct 2016 08:20
Last Modified: 01 Nov 2017 00:50
DOI or Identification number: 10.1002/ajhb.22934
URI: http://researchonline.ljmu.ac.uk/id/eprint/4269

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