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Phasmarhabditis hermaphrodita – a new model to study the genetic evolution of parasitism

Rae, RG (2017) Phasmarhabditis hermaphrodita – a new model to study the genetic evolution of parasitism. Nematology, 19 (3). ISSN 1568-5411

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Abstract

The evolutionary genetic mechanisms that are responsible for the transition of free-living nematodes to parasites are unknown and current nematode models used to study this have limitations. The gastropod parasite Phasmarhabditis hermaphrodita could be used as a new model to dissect the molecular mechanisms involved in the evolution of parasitism. Phasmarhabditis hermaphrodita is a facultative parasite of slugs and snails that can also be maintained easily under laboratory conditions like Caenorhabditis elegans and Pristionchus pacificus. Phasmarhabditis hermaphrodita and Phasmarhabditis species are easy to isolate from the wild and have been found around the world. The phylogenetic position of Phasmarhabditis is ideal for genomic comparison with other Clade 9 species such as C. elegans and P. pacificus, as well as mammalian and insect parasites. These attributes could make P. hermaphrodita an excellent choice of model to study the evolutionary emergence of parasitism.

Item Type: Article
Uncontrolled Keywords: 0608 Zoology
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QH Natural history > QH426 Genetics
Divisions: Natural Sciences and Psychology
Publisher: Brill Academic Publishers
Date Deposited: 04 Apr 2017 11:09
Last Modified: 12 Sep 2017 08:15
DOI or Identification number: 10.1163/15685411-00003053
URI: http://researchonline.ljmu.ac.uk/id/eprint/6209

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