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Antibacterial properties of biosurfactants against selected Gram-positive and -negative bacteria.

Diaz De Rienzo, MA and Stevenson, P and Marchant, R and Banat, IM (2016) Antibacterial properties of biosurfactants against selected Gram-positive and -negative bacteria. FEMS Microbiology Letters, 363 (2). ISSN 1574-6968

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Abstract

The antibacterial properties and ability to disrupt biofilms of biosurfactants (rhamnolipids, sophorolipids) and sodium dodecyl sulphate (SDS) in the presence and absence of selected organic acids were investigated. Pseudomonas aeruginosa PAO1 was inhibited by sophorolipids and SDS at concentrations >5% v/v, and the growth of Escherichia coli NCTC 10418 was also inhibited by sophorolipids and SDS at concentrations >5% and 0.1% v/v, respectively. Bacillus subtilis NCTC 10400 was inhibited by rhamnolipids, sophorolipids and SDS at concentrations >0.5% v/v of all three; the same effect was observed with Staphylococcus aureus ATCC 9144. The ability to attach to surfaces and biofilm formation of P. aeruginosa PAO1, E. coli NCTC 10418 and B. subtilis NCTC 10400 was inhibited by sophorolipids (1% v/v) in the presence of caprylic acid (0.8% v/v). In the case of S. aureus ATCC 9144, the best results were obtained using caprylic acid on its own. It was concluded that sophorolipids are promising compounds for the inhibition/disruption of biofilms formed by Gram-positive and Gram-negative microorganisms and this activity can be enhanced by the presence of booster compounds such as caprylic acid.

Item Type: Article
Additional Information: This article has been accepted for publication in FEMS Microbiology Letters Published by Oxford University Press.
Uncontrolled Keywords: 06 Biological Sciences, 11 Medical And Health Sciences, 07 Agricultural And Veterinary Sciences
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Pharmacy & Biomolecular Sciences
Publisher: Oxford University Press (OUP)
Related URLs:
Date Deposited: 28 Sep 2017 11:43
Last Modified: 28 Sep 2017 11:43
DOI or Identification number: 10.1093/femsle/fnv224
URI: http://researchonline.ljmu.ac.uk/id/eprint/7239

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