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Microbial biofilms: biosurfactants as antibiofilm agents.

Banat, IM, Diaz De Rienzo, MA and Quinn, GA (2014) Microbial biofilms: biosurfactants as antibiofilm agents. Applied Microbiology and Biotechnology, 98 (24). pp. 9915-9929. ISSN 0175-7598

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Current microbial inhibition strategies based on planktonic bacterial physiology have been known to have limited efficacy on the growth of biofilm communities. This problem can be exacerbated by the emergence of increasingly resistant clinical strains. All aspects of biofilm measurement, monitoring, dispersal, control, and inhibition are becoming issues of increasing importance. Biosurfactants have merited renewed interest in both clinical and hygienic sectors due to their potential to disperse microbial biofilms in addition to many other advantages. The dispersal properties of biosurfactants have been shown to rival those of conventional inhibitory agents against bacterial and yeast biofilms. This makes them suitable candidates for use in new generations of microbial dispersal agents and for use as adjuvants for existing microbial suppression or eradication strategies. In this review, we explore aspects of biofilm characteristics and examine the contribution of biologically derived surface-active agents (biosurfactants) to the disruption or inhibition of microbial biofilms.

Item Type: Article
Additional Information: This is a post-peer-review, pre-copyedit version of an article published in Applied Microbiology and Biotechnology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-014-6169-6
Uncontrolled Keywords: MD Multidisciplinary
Subjects: Q Science > QR Microbiology
Divisions: Pharmacy & Biomolecular Sciences
Publisher: Springer Verlag
Related URLs:
Date Deposited: 12 Mar 2018 11:31
Last Modified: 12 Mar 2018 11:31
DOI or Identification number: 10.1007/s00253-014-6169-6
URI: http://researchonline.ljmu.ac.uk/id/eprint/7241

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