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A prototype therapeutic capsule endoscope for ultrasound-mediated targeted drug delivery

Stewart, F, Verbeni, A, Qiu, Y, Cox, B, Vorstius, J, Newton, I, Huang, Z, Menciassi, A, Näthke, I and Cochran, S (2018) A prototype therapeutic capsule endoscope for ultrasound-mediated targeted drug delivery. Journal of Medical Robotics Research, 3 (2). ISSN 2424-905X

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Abstract

The prevalence of gastrointestinal (GI) diseases such as Crohn’s disease, which is chronic and incurable, are increasing worldwide. Treatment often involves potent drugs with unwanted side effects. The technological–pharmacological combination of capsule endoscopy with ultrasound-mediated targeted drug delivery (UmTDD) described in this paper carries new potential for treatment of these diseases throughout the GI tract. We describe a proof-of-concept UmTDD capsule and present preliminary results to demonstrate its promise as an autonomous tool to treat GI diseases.

Item Type: Article
Uncontrolled Keywords: Capsule endoscopy; therapy;; focused ultrasound; drug delivery; UmTDD; ultrasound capsule endoscopy (USCE)
Subjects: R Medicine > R Medicine (General)
T Technology > T Technology (General)
Divisions: Electronics and Electrical Engineering
Publisher: World Scientific Publishing Company
Date Deposited: 22 Aug 2018 08:01
Last Modified: 15 Sep 2018 05:07
DOI or Identification number: 10.1142/S2424905X18400019
URI: http://researchonline.ljmu.ac.uk/id/eprint/9062

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