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PARV4 found in wild chimpanzee faeces - alternate route of transmission?

Brožová, K, Modrý, D, Dadáková, E, Mapua, MI, Piel, AK, Stewart, FA, Celer, V and Hrazdilová, K PARV4 found in wild chimpanzee faeces - alternate route of transmission? Archives of Virology. ISSN 0304-8608 (Accepted)

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Abstract

Human parvovirus 4 (PARV4, family Parvoviridae, genus Tetraparvovirus) displays puzzling features, such as uncertain clinical importance/significance, unclear routes of transmission and discontinuous geographical distribution. The origin, or the general reservoir, of human PARV4 infection is unknown. We aimed to detect and characterize PARV4 virus in faecal samples collected from two wild chimpanzee populations and 19 species of captive nonhuman primates. We aimed to investigate these species as a potential reservoir and alternate route of transmission on the African continent. From almost 500 samples screened, a single wild Pan troglodytes schweinfurthii sample tested positive. Full genome analysis, as well as single ORF phylogenies, confirmed species-specific PARV4 infection.

Item Type: Article
Uncontrolled Keywords: 06 Biological Sciences, 11 Medical And Health Sciences, 07 Agricultural And Veterinary Sciences
Subjects: Q Science > QH Natural history
Q Science > QL Zoology
Divisions: Natural Sciences and Psychology
Publisher: Springer Verlag
Date Deposited: 03 Oct 2018 10:56
Last Modified: 03 Oct 2018 11:05
URI: http://researchonline.ljmu.ac.uk/id/eprint/9405

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