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Practice implications and recommendations for managing codeine misuse and dependence

Bergin, M, Norman, I, Foley, M, Harris, R, Rapca, A, Rich, E and van Hout, MC (2015) Practice implications and recommendations for managing codeine misuse and dependence. Acta Pharmaceutica, 65 (4). pp. 351-364. ISSN 1330-0075

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Abstract

Codeine, a weak opiate, requires increased pharmacovigilance relating to availability, heterogeneous nature of misuse, dependence and associated harm. A scoping review of literature on codeine was conducted using Arksey & O’Malley’s framework (1). Databases searched included PubMed, EBSCO Host, Science Direct, EMBASE, PsycINFO, Cochrane library and Medline from 1994 to 2014. Follow-up search strategies involved hand searching and searching of pharmaceutical, health, medical and drug related websites. Initial zscreening identified 3,105 articles with 475 meeting the inclusion criteria. Eight broad categories organised the literature, data charting and qualitative synthesis. This paper presents implications for practice and makes recommendations to address these issues. Themes identified relate to raising public and practitioner awareness, risk management, dispensing practices and monitoring and surveillance of codeine. Evidence to inform law enforcement, drug surveillance, public health initiatives, harm reduction approaches, pharmacy, clinical and treatment practices is warranted.

Item Type: Article
Uncontrolled Keywords: 1115 Pharmacology And Pharmaceutical Sciences
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RM Therapeutics. Pharmacology
Divisions: Public Health Institute
Publisher: De Gruyter Open
Related URLs:
Date Deposited: 21 Nov 2018 11:19
Last Modified: 21 Nov 2018 17:28
DOI or Identification number: 10.1515/acph-2015-0040
URI: http://researchonline.ljmu.ac.uk/id/eprint/9687

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