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Antimicrobial activity of endophytic fungi isolated from the mangrove plant Sonneratia apetala (Buch.-Ham) from the Sundarbans mangrove forest

Nurunnabi, TR, Sabrin, F, Sharif, DI, Nahar, L, Sohrab, MH, Sarker, SD, Rahman, SMM and Billah, MM (2020) Antimicrobial activity of endophytic fungi isolated from the mangrove plant Sonneratia apetala (Buch.-Ham) from the Sundarbans mangrove forest. Advances in Traditional Medicine. ISSN 2662-4052

Antimicrobial activity of Endophytic Fungi Isolated from the Mangrove Plant Sonneratia apetala (Buch.-Ham) from the Sundarbans Mangrove Forest.pdf - Accepted Version

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Endophytic fungi reside in the intercellular space of plant nourished by the plant. In return, they provide bioactive molecules which can play critical roles on plant defense system. Fifty six endophytes were isolated from the leaves, root, bark and fruits of Sonneratia apetala, a pioneer mangrove plant in the Sundarbans, Bangladesh. A total of 56 isolates were obtained and 12 different species within 8 genera were identified using morphological and molecular characteristics. Antimicrobial activity of Ethyl Acetate (EtOAc) and Methanolic (MeOH) extracts of these 12 different species were analyzed by resazurin assay and the Minimum Inhibitory Concentrations (MICs) were determined. The fungal extracts showed antimicrobial activities against more than one tested bacterium or fungus among 5 human pathogenic microbes, i.e. Escherichia coli NCTC 12241, Staphylococcus aureus NCTC 12981, Micrococcus lutus NCTC 7508, Pseudomonas aeruginosa NCTC 7508 and Candida albicans ATCC 90028. Overall, Methanolic extracts showed greater activity than that of Ethyl Acetate extracts. Of the isolates identified, Colletotrichum gloeosporioides, Aspergillus niger and Fusarium equiseti were the most active isolates and showed activity against microorganisms under investigation. Methanolic extracts of C. gloeosporioides and A. niger showed the lowest MIC (0.0024 mg/mL) against Pseudomonas aeruginosa. The study indicates that endophytic fungi isolated from S. apetala species posses potential antimicrobial properties, which could be further investigated.

Item Type: Article
Additional Information: This is a post-peer-review, pre-copyedit version of an article published in Advances in Traditional Medicine. The final authenticated version is available online at: http://dx.doi.org/10.1007/s13596-019-00422-9
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RS Pharmacy and materia medica
S Agriculture > SB Plant culture
Divisions: Pharmacy & Biomolecular Sciences
Publisher: Springer Nature
Date Deposited: 24 Jan 2020 10:01
Last Modified: 04 Sep 2021 08:04
DOI or ID number: 10.1007/s13596-019-00422-9
URI: https://researchonline.ljmu.ac.uk/id/eprint/12090
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