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Isoflavones-Based Liposome Formulations as Anti-Aging for Skincare

Hollmerus, S, Yousaf, SS, Islam, Y and Khan, I (2018) Isoflavones-Based Liposome Formulations as Anti-Aging for Skincare. Novel Approaches in Drug Designing & Development, 3 (3). ISSN 2575-8942

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Isoflavones commonly found in plants such as soya and red clover express many health benefits including skin healing and anti-aging properties. The capacity to counteract aging is due to isoflavones being both anti-oxidants as well as phytoestrogens, hence preventing both extrinsic as well as intrinsic aging processes. In skincare formulations their effects could be enhanced with the aid of advanced delivery systems. Isoflavones from soya bean source has successfully been incorporated into liposomes and further used in commercially available anti-aging creams. However different plants vary in isoflavone composition. Red clover isoflavones express less affinity for the estrogen receptor whilst simultaneously containing isoflavone structures that should be easier to encapsulate in liposome vehicles compared to soya bean derived isoflavones. If liposome entrapped isoflavones could successfully be obtained, the novel liposome could have a visible effect on the skin and reduce the visible adverse outcomes of aging and moreover be advantageous in terms of endocrinological safety and/or have a higher efficiency of delivering active when compared to the currently available products on the market.

Item Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Pharmacy & Biomolecular Sciences
Publisher: Juniper Publishers
Date Deposited: 08 Apr 2020 11:56
Last Modified: 04 Sep 2021 07:30
DOI or ID number: 10.19080/napdd.2018.03.555615
URI: https://researchonline.ljmu.ac.uk/id/eprint/12686
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