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The association between excess weight and COVID-19 outcomes: an umbrella review

Matu, Jamie, Griffiths, A, Shannon, O, Jones, A, Day, R, Radley, D, Feeley, A, Mabbs, L, Blackshaw, J, Sattar, N and Ells, L The association between excess weight and COVID-19 outcomes: an umbrella review. Obesity Reviews. ISSN 1467-7881 (Accepted)

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Abstract

This umbrella review assessed the association between excess weight and COVID19 outcomes. MEDLINE, PsycINFO and CINAHL were systematically searched for reviews which assessed the association between excess weight and COVID-19 outcomes. A second-order meta-analysis was conducted on the available data for intensive care unit admission, invasive mechanical ventilation administration, disease severity, hospitalisation, and mortality. The quality of included reviews was assessed using the AMSTAR-2 appraisal tool. In total, 52 systematic reviews were included, 49 of which included meta-analyses. The risk of severe outcomes (OR = 1.86; 95% CI: 1.70 to 2.05), intensive care unit admission (OR = 1.58; 95% CI: 1.45 to 1.72), invasive mechanical ventilation administration (OR = 1.70; 95% CI: 1.57 to 1.83), hospitalisation (OR = 1.82; 95% CI: 1.61 to 2.05), and mortality (OR = 1.35; 95% CI: 1.24 to 1.48) following COVID-19 infection was significantly higher in individuals living with excess weight compared to those with a healthy weight. There was limited evidence available in the included reviews regarding the influence of moderating factors such as ethnicity, and the majority of included reviews were of poor quality. Obesity appears to represent an important modifiable pre-infection risk factor for severe COVID-19 outcomes, including death.

Item Type: Article
Uncontrolled Keywords: 11 Medical and Health Sciences; 17 Psychology and Cognitive Sciences; Endocrinology & Metabolism
Subjects: B Philosophy. Psychology. Religion > BF Psychology
T Technology > TX Home economics > TX341 Nutrition. Foods and food supply
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Psychology (from Sep 2019)
Publisher: Wiley
SWORD Depositor: A Symplectic
Date Deposited: 08 Jul 2024 10:16
Last Modified: 08 Jul 2024 10:16
URI: https://researchonline.ljmu.ac.uk/id/eprint/23716
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