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Phytochemical and bioactivity evaluation of Scrophularia amplexicaulis Benth

Pasdaran, A, Delazar, A, Ayatollahi, M, Nahar, L and Sarker, SD (2016) Phytochemical and bioactivity evaluation of Scrophularia amplexicaulis Benth. Records of Natural Products, 10 (4). pp. 519-525. ISSN 1307-6167

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Scrophularia amplexicaulis Benth. is an Iranian endemic species of the genus Scrophularia, which comprises ca. 200 medicinally important herbaceous flowering plants. Phytochemical investigation of the methanol extract of the aerial parts of this species afforded two iridoid glycosides, scropolioside D (1) and scrophuloside B4 (2), and two phenylalkanoid glycosides, salidroside (3) and verbascoside (4). Structures of these compounds were determined by comprehensive spectroscopic analyses. Free-radical-scavenging activity, potential antimalarial property, and contact toxicity as well as general toxicity of the extract and fractions were assessed.

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Pharmacy & Biomolecular Sciences
Publisher: ACG Publications
Date Deposited: 29 Jan 2016 16:19
Last Modified: 04 Sep 2021 13:31
URI: https://researchonline.ljmu.ac.uk/id/eprint/2790
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