Pre- and post-discharge physical activity in acute myocardial infarction: Relation to clinical events across 5-year follow-up

Dijkman, R orcid iconORCID: 0009-0006-0233-6255, Kroesen, SH, van Bakel, BMA, van Geuns, RJM, Dimitriu-Leen, AC, Eijsvogels, TMH and Thijssen, DHJ orcid iconORCID: 0000-0002-7707-5567 (2026) Pre- and post-discharge physical activity in acute myocardial infarction: Relation to clinical events across 5-year follow-up. American Journal of Preventive Cardiology, 27. p. 101641. ISSN 2666-6677

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Abstract

Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide [1]. Increasing habitual physical activity (PA) is recommended in contemporary guidelines as it attenuates disease progression and improves clinical outcomes. However, exercise-based cardiac rehabilitation (CR) typically commences weeks to months after myocardial infarction (MI), leaving the immediate post-discharge period poorly defined regarding PA and its safety. Therefore, we examined the association between objectively measured post-discharge PA and short-term major adverse cardiovascular events (MACE) at 1-, 3-, and 6-months follow-up in patients recovering from MI. In addition, we explored the relationship between pre-admission PA and post-discharge PA, and assessed their associations with long-term (5-year) MACE.

Item Type: Article
Uncontrolled Keywords: 32 Biomedical and Clinical Sciences; 3201 Cardiovascular Medicine and Haematology; Heart Disease - Coronary Heart Disease; Cardiovascular; Clinical Research; Prevention; Physical Activity; Heart Disease; Cardiovascular; 3201 Cardiovascular medicine and haematology
Subjects: R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Sport and Exercise Sciences
Publisher: Elsevier
Date of acceptance: 16 April 2026
Date of first compliant Open Access: 10 July 2026
Date Deposited: 10 Jul 2026 09:11
Last Modified: 10 Jul 2026 09:11
DOI or ID number: 10.1016/j.ajpc.2026.101641
URI: https://researchonline.ljmu.ac.uk/id/eprint/28988
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