Article

Lund, M, Heaton, R, Hargreaves, IP, Gregersen, N and Olsen, RKJ (2022) Odd- and even-numbered medium-chained fatty acids protect against glutathione depletion in very long-chain acyl-CoA dehydrogenase deficiency. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1868 (2). ISSN 1388-1981

Jurkute, N, Cancellieri, F, Pohl, L, Li, CHZ, Heaton, R, Reurink, J, Bellingham, J, Quinodoz, M, Yioti, G, Stefaniotou, M, Weener, M, Zuleger, T, Haack, TB, Stingl, K, Hoyng, CB, Mahroo, OA, Hargreaves, IP, Raymond, FL, Michaelides, M, Rivolta, C et al, Kohl, S, Roosing, S, Webster, AR and Arno, G (2022) Biallelic variants in coenzyme Q10 biosynthesis pathway genes cause a retinitis pigmentosa phenotype. Genomic Medicine, 7. ISSN 1871-7934

Heaton, R, Martin, H, Chadee, A, Milling, A, Dunne, S and Borthwick, F (2022) The Construction Materials Conundrum: Practical Solutions to Address Integrated Supply Chain Complexities. Journal of Construction Engineering and Management, 148 (8). ISSN 0733-9364

Mantle, D, Heaton, R and Hargreaves, IP (2021) Coenzyme Q10 and Immune Function: An Overview. Antioxidants, 10 (5). ISSN 2076-3921

Lund, M, Andersen, KG, Heaton, R, Hargreaves, IP, Gregersen, N and Olsen, RKJ (2021) Bezafibrate activation of PPAR drives disturbances in mitochondrial redox bioenergetics and decreases the viability of cells from patients with VLCAD deficiency. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. ISSN 0925-4439

Maguire, A, Mooney, C, Flynn, G, Ferguson, Y, O'Keane, V, O'Rourke, D, McMonagle, T, Heaton, R, Phillips, S, Hargreaves, IP, Gill, M and Hargreaves, A (2021) No Effect of Coenzyme Q10 on Cognitive Function, Psychological Symptoms, and Health-related Outcomes in Schizophrenia and Schizoaffective Disorder. Journal of Clinical Psychopharmacology, 41 (1). pp. 53-57. ISSN 0271-0749

Proctor, EC, Turton, N, Boan, EJ, Bennett, E, Philips, S, Heaton, R and Hargreaves, I (2020) The Effect of Methylmalonic Acid Treatment on Human Neuronal Cell Coenzyme Q10 Status and Mitochondrial Function. International Journal of Molecular Sciences, 21 (23). ISSN 1422-0067

Ruiz, AJ, Tibary, A, Heaton, R, Hargreaves, IP, Leadon, DP and Bayly, WM (2020) Effects of Feeding Coenzyme Q10-Ubiquinol on Plasma Coenzyme Q10 Concentrations and Semen Quality in Stallions. Journal of Equine Veterinary Science, 96. ISSN 0737-0806

Stepien, KM, Roncaroli, F, Turton, N, Hendriksz, CJ, Roberts, M, Heaton, R and Hargreaves, IP (2020) Mechanisms of Mitochondrial Dysfunction in Lysosomal Storage Disorders: A Review. Journal of Clinical Medicine, 9 (8). ISSN 2077-0383

Heaton, R, Heales, S, Rahman, K, Sexton, DW and Hargreaves, IP (2020) The Effect of Cellular Coenzyme Q10 Deficiency on Lysosomal Acidification. Journal of Clinical Medicine, 9 (6). ISSN 2077-0383

Ghosh, R, Wood-Kaczmar, A, Dobson, L, Smith, EJ, Sirinathsinghji, EC, Kriston-Vizi, J, Hargreaves, I, Heaton, R, Hermann, F, Abramov, AY, Lamb, AJ, Heales, SJ, Kettler, R, Bates, GP, Andre, R and Tabrizi, SJ (2020) Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction. The FASEB Journal. ISSN 0892-6638

Turton, N, Heaton, R, Ismail, F, Roberts, S, Nelder, S, Phillips, S and Hargreaves, IP (2020) The Effect of Organophosphate Exposure on Neuronal Cell Coenzyme Q10 Status. Neurochemical Research. ISSN 0364-3190

Ceresa, C, Hutton, S, Lajarin-Cuesta, M, Heaton, R, Hargreaves, IP, Fracchia, L and Diaz De Rienzo, MA (2020) Production of Mannosylerythritol Lipids (MELs) to be Used as Antimicrobial Agents against S. aureus ATCC 6538. Current Microbiology, 77. pp. 1373-1380. ISSN 0343-8651

Heaton, R, Millichap, L, Saleem, F, Gannon, J, Begum, G and Hargreaves, IP (2019) Current biochemical treatments of mitochondrial respiratory chain disorders. Expert Opinion on Orphan Drugs, 7 (6). pp. 277-285. ISSN 2167-8707

Stepien, KM, Heaton, R, Rankin, S, Murphy, A, Bentley, J, Sexton, DW and Hargreaves, IP (2017) Evidence of Oxidative Stress and Secondary Mitochondrial Dysfunction in Metabolic and Non-Metabolic Disorders. Journal of Clinical Medicine, 6 (7). ISSN 2077-0383

Book Section

Heaton, R, Duberley, K and Hargreaves, IP (2020) Coenzyme Q10 Assessment and the Establishment of a Neuronal Cell Model of CoQ10 Deficiency. In: guest, P, (ed.) Clinical and Preclinical Models for Maximizing Healthspan. Springer, pp. 277-287. ISBN 978-1-07-160471-7

Thesis

Heaton, R (2022) CoQ10 Deficiency: The Lysosomal Paradigm. Doctoral thesis, Liverpool John Moores University.