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Lipid droplet detection by the cavity perturbation method

Blakey, RT and Mason, A and Rolph, CE and Bond, G and Al-Shamma'a, A (2011) Lipid droplet detection by the cavity perturbation method. In: Journal of Physics Conference Series , 307 (1). pp. 1-5. (16th Conference in the Biennial Sensors and their Applications, 12th - 14th September 2011, Univ Coll Cork, Tyndall Natl Inst, Cork, IRELAND).

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Abstract

There are currently no point-of-care diagnosis strategies available to indicate the presence of neoplasmic growth. This research aims to develop a novel diagnostic strategy based on detecting TAG accumulation in cells. This element of the research is a preliminary experiment to prove the concept of detecting TAG lipid droplets in YEPD media. It was found that a change in mono-unsaturated concentration can be detected by the frequency shift in a resonant cavity. The dielectric constant of TAG vegetable oils was calculated at 2.34-2.39. It was also found that concentrations of lipid droplet can be differentiated up to 5% (v/v).

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: 02 Physical Sciences, 09 Engineering
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
T Technology > TP Chemical technology
Divisions: Built Environment
Publisher: IOP PUBLISHING LTD
Related URLs:
Date Deposited: 11 Feb 2016 13:49
Last Modified: 11 Feb 2016 13:49
DOI or Identification number: 10.1088/1742-6596/307/1/012021
Editors: Kyriacou, PA and O'Riordan, A and McConnell, G
URI: http://researchonline.ljmu.ac.uk/id/eprint/2913

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