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Melilotoside derivatives from Artemisia splendens (Asteraceae)

Afshar, FH and Delazar, A and Nazemiyeh, H and Nahar, L and Moghaddam, SB and Mbaebie, BO and Gibbons, S and Sarker, SD (2017) Melilotoside derivatives from Artemisia splendens (Asteraceae). Records of Natural Products, 11 (1). pp. 43-50. ISSN 1307-6167

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Abstract

All rights reserved.A combination of solid-phase-extraction (SPE) and reversed-phase preparative high-performance liquid chromatography (prep-HPLC) of the methanolic extract of the aerial parts of Artemisia splendens (common name: “Asia Minor Wormwood”), an endemic Iranian species, afforded Z- and E-melilotosides (1 and 2), Z- and E-4-methoxy-melilotosides (3 and 4), and a new dimer, bis-ortho-Z-melilotoside (5, named: splendenoside). Whilst the structures of these compounds (1-5) were elucidated unequivocally by spectroscopic means, the in vitro free-radical-scavenging property of 1-5 was determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. This is the first report on the occurrence of any melilotoside derivatives in the genus Artemisia. © 2016 ACG Publications.

Item Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Pharmacy & Biomolecular Sciences
Publisher: ACG Publications
Date Deposited: 17 Oct 2016 11:05
Last Modified: 06 Sep 2017 16:26
URI: http://researchonline.ljmu.ac.uk/id/eprint/4625

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