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Childhood body weight in relation to morbidity from cardiovascular disease and cancer in older adulthood: 67-year follow-up of participants in the 1947 Scottish Mental Survey.

Batty, GD and Calvin, CM and Brett, CE and Čukić, I and Deary, IJ (2015) Childhood body weight in relation to morbidity from cardiovascular disease and cancer in older adulthood: 67-year follow-up of participants in the 1947 Scottish Mental Survey. American Journal of Epidemiology, 182 (9). ISSN 1476-6256

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Abstract

Although it has been well documented that elevated body weight in middle- and older-aged populations is associated with multiple morbidities, the influence of childhood body weight on health endpoints other than coronary heart disease is not well understood. Accordingly, using a subsample of 4,620 participants (2,288 women) from the Scottish Mental Survey of 1947, we examined the association between body mass index measured at 11 years of age and future risk of 9 independent health endpoints as ascertained from national hospital admissions and cancer registers until 2014 (up to age 77 years). Although there was some evidence of a relationship between elevated childhood body mass index and higher rates of peripheral vascular disease (per each 1-standard deviation increase in body mass index, hazard ratio = 1.21, 95% confidence interval: 1.07, 1.37) and smoking-related cancers (per each 1-standard deviation increase in body mass index, hazard ratio = 1.09, 95% confidence interval: 1.01, 1.17), there was no apparent association with coronary heart disease, stroke (including ischemic stroke), heart failure, or carcinomas of the colorectum, stomach, lung, prostate, or breast. In conclusion, a relationship between childhood body weight and later morbidity was largely lacking in the present study.

Item Type: Article
Additional Information: This is a pre-copyedited, author-produced version of an article accepted for publication in American Journal of Epidemiology following peer review. The version of record G. David Batty, Catherine M. Calvin, Caroline E. Brett, Iva Čukić, Ian J. Deary; Childhood Body Weight in Relation to Morbidity From Cardiovascular Disease and Cancer in Older Adulthood: 67-Year Follow-up of Participants in the 1947 Scottish Mental Survey. Am J Epidemiol 2015; 182 (9): 775-780. doi: 10.1093/aje/kwv154 is available online at: http://dx.doi.org/10.1093/aje/kwv154
Uncontrolled Keywords: 11 Medical And Health Sciences, 01 Mathematical Sciences
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services
Divisions: Sport & Exercise Sciences
Publisher: Oxford University Press
Related URLs:
Date Deposited: 14 Jun 2017 08:46
Last Modified: 14 Jun 2017 08:46
DOI or Identification number: 10.1093/aje/kwv154
URI: http://researchonline.ljmu.ac.uk/id/eprint/6692

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