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Chronic kidney disease and coenzyme Q10 supplementation

Hargreaves, IP, Mantle, D and Milford, D (2019) Chronic kidney disease and coenzyme Q10 supplementation. Journal of Kidney Care, 4 (2). pp. 82-90. ISSN 2397-9534

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Abstract

Among the potential causes of chronic kidney disease (CKD), mitochondrial respiratory chain (MRC) dysfunction, oxidative stress and inflammation have been implicated as contributor factors to the pathogenesis of this disorder. It is thought that CoQ10 supplementation may offer some therapeutic potential in the treatment of patients with CKD, since CoQ10 has a key role in normal MRC function, as well as having antioxidant and anti-inflammatory action. This article will outline the current knowledge on the use of CoQ10 in the treatment of CKD

Item Type: Article
Additional Information: This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Kidney Care, copyright © MA Healthcare, after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.12968/jokc.2019.4.2.82
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Pharmacy & Biomolecular Sciences
Publisher: Mark Allen Group
Date Deposited: 02 Apr 2019 09:14
Last Modified: 02 Sep 2019 08:00
DOI or Identification number: 10.12968/jokc.2019.4.2.82
URI: https://researchonline.ljmu.ac.uk/id/eprint/10461

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