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Globrauneine A–F: six new triterpenoid esters from the leaves of Globimetula braunii

Muhammad, KJA, Jamil, S, Basar, N, Sarker, SD and Mohammed, MG (2019) Globrauneine A–F: six new triterpenoid esters from the leaves of Globimetula braunii. Natural Product Research. ISSN 1478-6419

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Abstract

Phytochemical study was conducted on the leaves of Globimetula braunii which is a hemi parasitic plant belonging to the family Loranthaceae. Extraction was carried out using cold extraction method with increasing polarity of solvents i.e n-hexane, CH2Cl2 and MeOH. The components were separated by chromatographic technique and the structures of the compounds were elucidated by extensive spectroscopic analyses including MS, FTIR, 1D and 2D NMR, HRMS and chemical methods. Six new pentacyclic triterpenoid esters named as globrauneine A (1), globrauneine B (2), globrauneine C (3), globrauneine D (4), globrauneine E (5), and globrauneine F (6), together with six known compounds (7 – 12) were successfully isolated from the leaves of G. braunii growing on Piliostigma thonningii. These results depict a substantial support to the chemotaxonomy of the genus Globimetula.

Item Type: Article
Additional Information: This is an Accepted Manuscript of an article published by Taylor & Francis in Natural Product Research on 31/3/19, available online: http://www.tandfonline.com/10.1080/14786419.2019.1586693
Uncontrolled Keywords: MD Multidisciplinary
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Pharmacy & Biomolecular Sciences
Publisher: Taylor & Francis
Date Deposited: 04 Apr 2019 09:32
Last Modified: 04 Sep 2021 09:32
DOI or ID number: 10.1080/14786419.2019.1586693
URI: https://researchonline.ljmu.ac.uk/id/eprint/10490
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