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Ecstasy-related deficits in the updating component of executive processes

Montgomery, C and Fisk, JE (2008) Ecstasy-related deficits in the updating component of executive processes. Human Psychopharmacology: Clinical and Experimental, 23 (6). pp. 495-511. ISSN 0885-6222

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Research shows that users of ecstasy (MDMA) exhibit deficits in executive processes. The updating component appears to be particularly susceptible. Less is known about the precise nature of such deficits. The present study sought to determine if ecstasy-related deficits in memory updating are related to serial position of items presented, or length of the list of items.

Seventy-three ecstasy/polydrug users and seventy-three non-ecstasy users completed tasks of verbal and spatial memory running memory, recalling the most recent items, in lists of varying and unknown length. Participants were categorised according to letter and spatial span (four, five or six), producing six sub-samples for analysis.

Ecstasy-polydrug users were impaired in four out of the six sub-sample analyses. Three of these were due to impaired recall of earlier serial positions.

The results of the present study provide further support for updating deficits in ecstasy-polydrug users. The results are suggestive of a breakdown in the maintenance of information in working memory in terms of chunking; it appears that ecstasy/polydrug users are as able as non-ecstasy users to form memory ‘chunks’ from the items, but that such chunks are not retained as effectively.

Item Type: Article
Additional Information: This is the peer reviewed version of the following article: Montgomery, C. and Fisk, J. E. (2008), Ecstasy-related deficits in the updating component of executive processes. Hum. Psychopharmacol. Clin. Exp., 23: 495–511, which has been published in final form at http://dx.doi.org/10.1002/hup.951. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."
Uncontrolled Keywords: 1115 Pharmacology And Pharmaceutical Sciences, 1701 Psychology, 1702 Cognitive Science
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RM Therapeutics. Pharmacology
Divisions: Natural Sciences & Psychology (closed 31 Aug 19)
Publisher: Wiley
Related URLs:
Date Deposited: 15 May 2015 11:18
Last Modified: 04 Sep 2021 14:22
DOI or ID number: 10.1002/hup.951
URI: https://researchonline.ljmu.ac.uk/id/eprint/1102
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