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Hepatitis C prevalence in Denmark -an estimate based on multiple national registers

Christensen, PB, Hay, G, Jepsen, P, Omland, LH, Just, SA, Krarup, HB, Weis, N, Obel, N and Cowan, S (2012) Hepatitis C prevalence in Denmark -an estimate based on multiple national registers. BMC Infectious Diseases, 12. ISSN 1471-2334

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Abstract

Background: A national survey for chronic hepatitis C has not been performed in Denmark and the prevalence is unknown. Our aim was to estimate the prevalence of chronic hepatitis C from public registers and the proportion of these patients who received specialized healthcare.
Methods: Patients with a diagnosis of chronic hepatitis C were identified from four national registers: a laboratory register, the Hospital Discharge Register, a clinical database of chronic viral hepatitis and the Register of Communicable Diseases. The total population diagnosed with hepatitis C was estimated by capture-recapture analysis. The population with undiagnosed hepatitis C was derived from the national register of drug users by comparing diagnosed and tested persons.
Results: A total of 6,935 patients diagnosed with chronic hepatitis C were identified in the four registers and the estimated population diagnosed with the disease was 9,166 persons (95% C.I. interval 8,973 – 9,877), corresponding to 0.21% (95% CI 0.21%-0.23%) of the Danish population over 15years of age. The prevalence was highest among persons 40–49years old (0.39%) and males (0.28%). It was estimated that 40% of the diagnosed patients lived in the capital region, and 33.5% had attended specialised healthcare. It was estimated that 46% of hepatitis C patients had not been diagnosed and the total population with chronic hepatitis C in Denmark was 16,888 (95% C.I. 16,474-18,287), corresponding to 0.38% (95% CI 0.37-0.42) of the population over 15years of age.
Conclusions: The estimated prevalence of chronic hepatitis C in Denmark was 0.38%. Less than half of the patients with chronic hepatitis C in Denmark have been identified and among these patients, one in three has attended specialised care.

Item Type: Article
Uncontrolled Keywords: 0605 Microbiology, 1103 Clinical Sciences, 1108 Medical Microbiology
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Public Health Institute
Publisher: BioMed Central
Related URLs:
Date Deposited: 03 Mar 2020 09:48
Last Modified: 03 Mar 2020 10:00
DOI or Identification number: 10.1186/1471-2334-12-178
URI: http://researchonline.ljmu.ac.uk/id/eprint/12362

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