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Exercise Training Increases Serum Cardiac Troponin T Independent of Left Ventricular Mass.

Kong, Z, Zhang, H, Nie, J, Wen, L, Shi, Q, Ng, SF, Huang, C and George, KP (2021) Exercise Training Increases Serum Cardiac Troponin T Independent of Left Ventricular Mass. International Journal of Sports Medicine. ISSN 0172-4622

Exercise training increases resting circulating cardiac troponin T independent of changes in left ventricular mass.pdf - Accepted Version

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The purpose of this study was to determine whether exercise training mediated cardiac troponin T (cTnT) and whether this was associated with increases in left ventricular mass (LVM). Fifty-four sedentary obese women were randomised to high-intensity interval training (HIIT, repeated 4-min cycling at 90% V̇O2max interspersed with 3-min rest), work-equivalent continuous aerobic training (CAT, continuous cycling at 60% V̇O2max) or a control group (CON). Resting serum cTnT was assessed using a high-sensitivity assay before and after 12 weeks of training. LVM was determined from 2D echocardiography at the same timepoints. Both HIIT and CAT induced a similar elevation (median 3.07 to 3.76 ng.l-1, p<0.05) in resting cTnT compared with pre-training and the CON (3.49 to 3.45 ng.l-1, p>0.05). LVM index in HIIT increased (62.2±7.8 to 73.1±14.1 g.m-2, p<0.05), but not in CAT (66.1±9.7 to 67.6±9.6 g.m-2, p>0.05) and CON (67.9±9.5 to 70.2±9.1 g.m-2, p>0.05). Training-induced changes in resting cTnT did not correlate with changes in LVM index (r=-0.025, p=0.857). These findings suggest that twelve weeks of either HIIT or CAT increased resting cTnT, but the effects were independent of any changes in LVM in sedentary obese women.

Item Type: Article
Uncontrolled Keywords: 0913 Mechanical Engineering, 1106 Human Movement and Sports Sciences
Subjects: R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Sport & Exercise Sciences
Publisher: Georg Thieme Verlag
Related URLs:
Date Deposited: 14 Dec 2021 10:13
Last Modified: 06 Dec 2022 00:50
DOI or ID number: 10.1055/a-1670-7707
URI: https://researchonline.ljmu.ac.uk/id/eprint/15920
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