Healthy Brain Study consortium, , Aarts, E, Akkerman, A, Altgassen, M, Bartels, R, Beckers, D, Bevelander, K, Bijleveld, E, Davidson, EB, Boleij, A, Bralten, J, Cillessen, T, Claassen, J, Cools, R, Cornelissen, I, Dresler, M, Eijsvogels, T, Faber, M, Fernández, G, Figner, B et al, Fritsche, M, Füllbrunn, S, Gayet, S, van Gelder, MMHJ, van Gerven, M, Geurts, S, Greven, CU, Groefsema, M, Haak, K, Hagoort, P, Hartman, Y, van der Heijden, B, Hermans, E, Heuvelmans, V, Hintz, F, den Hollander, J, Hulsman, AM, Idesis, S, Jaeger, M, Janse, E, Janzing, J, Kessels, RPC, Karremans, JC, de Kleijn, W, Klein, M, Klumpers, F, Kohn, N, Korzilius, H, Krahmer, B, de Lange, F, van Leeuwen, J, Liu, H, Luijten, M, Manders, P, Manevska, K, Marques, JP, Matthews, J, McQueen, JM, Medendorp, P, Melis, R, Meyer, A, Oosterman, J, Overbeek, L, Peelen, M, Popma, J, Postma, G, Roelofs, K, van Rossenberg, YGT, Schaap, G, Scheepers, P, Selen, L, Starren, M, Swinkels, DW, Tendolkar, I, Thijssen, DHJ, Timmerman, H, Tutunji, R, Tuladhar, A, Veling, H, Verhagen, M, Verkroost, J, Vink, J, Vriezekolk, V, Vrijsen, J, Vyrastekova, J, van der Wal, S, Willems, R and Willemsen, A (2021) Protocol of the Healthy Brain Study: An accessible resource for understanding the human brain and how it dynamically and individually operates in its bio-social context. PLoS One, 16 (12). pp. 1-27. ISSN 1932-6203

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Abstract

The endeavor to understand the human brain has seen more progress in the last few decades than in the previous two millennia. Still, our understanding of how the human brain relates to behavior in the real world and how this link is modulated by biological, social, and environmental factors is limited. To address this, we designed the Healthy Brain Study (HBS), an interdisciplinary, longitudinal, cohort study based on multidimensional, dynamic assessments in both the laboratory and the real world. Here, we describe the rationale and design of the currently ongoing HBS. The HBS is examining a population-based sample of 1,000 healthy participants (age 30-39) who are thoroughly studied across an entire year. Data are collected through cognitive, affective, behavioral, and physiological testing, neuroimaging, bio-sampling, questionnaires, ecological momentary assessment, and real-world assessments using wearable devices. These data will become an accessible resource for the scientific community enabling the next step in understanding the human brain and how it dynamically and individually operates in its bio-social context. An access procedure to the collected data and bio-samples is in place and published on https://www.healthybrainstudy.nl/en/data-and-methods/access. Trail registration: https://www.trialregister.nl/trial/7955.

Item Type:	Article
Uncontrolled Keywords:	Adult; Affect; Behavior; Brain; COVID-19; Cognition; Female; Humans; Male; Neuroimaging; Sensation; Social Environment; Surveys and Questionnaires
Subjects:	B Philosophy. Psychology. Religion > BF Psychology Q Science > QH Natural history > QH301 Biology Q Science > QP Physiology R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions:	Sport & Exercise Sciences
Publisher:	Public Library of Science
Related URLs:	https://www.ncbi.nlm.nih.gov/pubmed/34965252
Date Deposited:	12 Apr 2022 13:54
Last Modified:	12 Apr 2022 13:54
DOI or ID number:	10.1371/journal.pone.0260952
URI:	https://researchonline.ljmu.ac.uk/id/eprint/16648

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