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Pollack, E, Johnston, S, Petraiuolo, WJ, Roy, S and Galvain, T (2021) Economic analysis of leak complications in anastomoses performed with powered versus manual circular staplers in left-sided colorectal resections: A us-based cost analysis. ClinicoEconomics and Outcomes Research, 13. pp. 531-540. ISSN 1178-6981
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Economic analysis of leak complications in anastomoses performed with powered.pdf - Published Version Available under License Creative Commons Attribution Non-commercial. Download (4MB) | Preview |
Abstract
Purpose: To estimate the cost impact of using the ECHELON CIRCULAR™ Powered Stapler (ECP) compared with manual circular staplers (standard of care, SOC) among patients undergoing colectomy procedures that involve left-sided anastomosis. Methods: A US hospital-based budget impact model was developed to estimate the impact of ECP in reducing the surgical complication of anastomotic leak. The incremental acquisition cost of ECP vs SOC was compared to the net potential savings from reduced complication costs. The model was based on complication rates from a recently published matching-adjusted indirect comparison (MAIC) that compared clinical and healthcare utilization outcomes of patients using ECP with those of a propensity score-matched retrospective SOC control cohort from a real-world clinical practice population. The model assessed total cost, average length of stay (LOS), proportion of patients with a non-home discharge, and all-cause readmission. Deterministic (DSA) and probabilistic sensitivity analyses (PSA) were conducted to evaluate the robustness of the model assumptions and inputs. Results: Despite a higher device cost of $412 for ECP compared with $298 for a manual stapler, annual savings due to avoided complications with ECP was $53,987 for anastomotic leak, assuming 100 procedures per year with each type of circular stapler. ECP also helped to avoid 27 LOS days, 0.38 readmissions and 0.22 non-home discharges. Sensitivity analyses around potential drivers of costs established the robustness of economic savings with the use of ECP – with annual savings being most impacted by the probability of anastomotic leak complication in the DSA. Conclusion: This model demonstrates that among patients undergoing left-sided colectomy procedures, the incremental cost of using the ECHELON CIRCULAR™ Powered Stapler instead of a manual circular stapler was offset by the savings from lowered incidence and cost of management of anastomotic leaks in the hospital setting.
| Item Type: | Article |
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| Uncontrolled Keywords: | anastomotic leak; circular stapler; colectomy; costs; outcomes; 1117 Public Health and Health Services |
| Subjects: | H Social Sciences > HG Finance Q Science > QA Mathematics > QA75 Electronic computers. Computer science R Medicine > R Medicine (General) |
| Divisions: | Computer Science & Mathematics |
| Publisher: | Dove Press |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 12 May 2022 09:51 |
| Last Modified: | 12 May 2022 10:00 |
| DOI or ID number: | 10.2147/CEOR.S305296 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/16809 |
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