Epidemiologic characteristics, clinical management, and public health implications of Coronavirus Disease 2019 (COVID-19) in pregnancy: A Systematic Review and Meta-analysis.

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Sathian, B orcid iconORCID: 0000-0003-0851-4762, Banerjee, I orcid iconORCID: 0000-0003-2880-4695, Mekkodathil, AA orcid iconORCID: 0000-0001-8431-8937, van Teijlingen, ER orcid iconORCID: 0000-0001-5523-8583, Pizarro, AB orcid iconORCID: 0000-0003-4089-454X, Asim, M, Mancha, MA, Kabir, R orcid iconORCID: 0000-0001-9257-2775, Simkhada, PP orcid iconORCID: 0000-0002-5706-6479, do Nascimento, IJB and Al Hamad, H (2021) Epidemiologic characteristics, clinical management, and public health implications of Coronavirus Disease 2019 (COVID-19) in pregnancy: A Systematic Review and Meta-analysis. Nepal Journal of Epidemiology, 11 (4). pp. 1103-1125. ISSN 2091-0800

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Epidemiologic characteristics, clinical management, and public health implications of Coronavirus Disease 2019 (COVID-19) in pregnancy.pdf - Published Version
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Open Access URL: https://doi.org/10.3126/nje.v11i4.41911 (Published version)

Abstract

Background: The novel coronavirus disease 2019 (COVID-19) outbreak, caused by the pathogenic severe acute respiratory syndrome-2 (SARS-CoV-2) virus, is exponentially spreading across the globe.
Methods: The current systematic review was performed utilizing electronic databases i.e. PubMed, MEDLINE and EMBASE. We searched for the keywords "COVID-19 AND "pregnancy" between January 1st, 2020 until December 31, 2020.
Results: Out of 4005 records which were identified, 36 original studies were included in this systematic review. Pooled prevalence of vertical transmission was 10%, 95% CI: 4-17%. Pooled prevalence of neonatal mortality was 7%, 95% CI: 0-21%.
Conclusion: The contemporary evidence suggests that the incubation period of COVID-19 is 2-14 days, and this infection could be transmitted even from the infected asymptomatic individuals. It is found that the clinical presentation of pregnant women with COVID-19 infection is comparable with the infected non-pregnant females, and the frequent symptoms were fever, cough, myalgia, sore throat and malaise. There are some cases with severe maternal morbidity and perinatal deaths secondary to COVID-19 infection. Under these circumstances, the pregnant women should focus on maintaining personal hygiene, proper nutrition and extreme social distancing to reduce the risk of COVID-19. Therefore, a systematic data reporting for evidence base clinical assessment, management and pregnancy outcomes is essential for prevention of COVID-19 infection among pregnant women.

Item Type: Article
Uncontrolled Keywords: Childbirth; Clinical Management; Complications; Pandemic; Pregnancy; Prevention
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RG Gynecology and obstetrics
Divisions: Public and Allied Health
Publisher: Manipal College of Medical Sciences
Date of acceptance: 3 October 2021
Date of first compliant Open Access: 29 July 2022
Date Deposited: 29 Jul 2022 12:13
Last Modified: 05 Jul 2025 14:45
DOI or ID number: 10.3126/nje.v11i4.41911
URI: https://researchonline.ljmu.ac.uk/id/eprint/17294
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