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Sathian, B, Banerjee, I, Mekkodathil, AA, van Teijlingen, ER, Pizarro, AB, Asim, M, Mancha, MA, Kabir, R, Simkhada, PP, do Nascimento, IJB and Al Hamad, H (2021) Epidemiologic characteristics, clinical management, and public health implications of Coronavirus Disease 2019 (COVID-19) in pregnancy: A Systematic Review and Meta-analysis. Nepal Journal of Epidemiology, 11 (4). pp. 1103-1125. ISSN 2091-0800
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Epidemiologic characteristics, clinical management, and public health implications of Coronavirus Disease 2019 (COVID-19) in pregnancy.pdf - Published Version Available under License Creative Commons Attribution. Download (1MB) | Preview |
Abstract
Background: The novel coronavirus disease 2019 (COVID-19) outbreak, caused by the pathogenic severe acute respiratory syndrome-2 (SARS-CoV-2) virus, is exponentially spreading across the globe.
Methods: The current systematic review was performed utilizing electronic databases i.e. PubMed, MEDLINE and EMBASE. We searched for the keywords "COVID-19 AND "pregnancy" between January 1st, 2020 until December 31, 2020.
Results: Out of 4005 records which were identified, 36 original studies were included in this systematic review. Pooled prevalence of vertical transmission was 10%, 95% CI: 4-17%. Pooled prevalence of neonatal mortality was 7%, 95% CI: 0-21%.
Conclusion: The contemporary evidence suggests that the incubation period of COVID-19 is 2-14 days, and this infection could be transmitted even from the infected asymptomatic individuals. It is found that the clinical presentation of pregnant women with COVID-19 infection is comparable with the infected non-pregnant females, and the frequent symptoms were fever, cough, myalgia, sore throat and malaise. There are some cases with severe maternal morbidity and perinatal deaths secondary to COVID-19 infection. Under these circumstances, the pregnant women should focus on maintaining personal hygiene, proper nutrition and extreme social distancing to reduce the risk of COVID-19. Therefore, a systematic data reporting for evidence base clinical assessment, management and pregnancy outcomes is essential for prevention of COVID-19 infection among pregnant women.
| Item Type: | Article |
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| Uncontrolled Keywords: | Childbirth; Clinical Management; Complications; Pandemic; Pregnancy; Prevention |
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RG Gynecology and obstetrics |
| Divisions: | Public Health Institute |
| Publisher: | Manipal College of Medical Sciences |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 29 Jul 2022 12:13 |
| Last Modified: | 29 Jul 2022 12:15 |
| DOI or Identification number: | 10.3126/nje.v11i4.41911 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/17294 |
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