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Increasing prevalence of chronic hepatitis B virus infection and low linkage to care in Denmark on 31 December 2016 - an update based on nationwide registers.

Bollerup, S, Wessman, M, Hansen, JF, Nielsen, S, Hay, G, Cowan, S, Krarup, HB, Omland, L, Jepsen, P, Weis, N and Christensen, PB (2022) Increasing prevalence of chronic hepatitis B virus infection and low linkage to care in Denmark on 31 December 2016 - an update based on nationwide registers. Infectious diseases. pp. 1-10. ISSN 2374-4235

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Abstract

We aimed to update the estimated prevalence of both diagnosed and undiagnosed chronic hepatitis B virus infection in Denmark. Moreover, we aimed to determine the number of people with chronic hepatitis B virus infection in specialised care and to assess the completeness of reporting to the national register of communicable diseases.
Methods: Using four registers with national coverage, we identified all individuals registered with chronic hepatitis B virus infection, aged 16 years or older, and alive in Denmark on 31 December 2016. The diagnosed population was then estimated using capture-recapture analysis. The undiagnosed population was estimated using data from the Danish pregnancy screening program.
Results: We estimated that 14,548 individuals were living with chronic hepatitis B virus infection corresponding to 0.3% of the Danish population. Of them, 13,530 (93%) were diagnosed and 7942 (55%) were registered in one or more of the source registers. Only 4297 (32%) diagnosed individuals had attended specialised care and only 3289 cases (24%) were reported to the Danish communicable disease register.
Conclusion: The prevalence of chronic hepatitis B virus infection increased from 2007 to 2017. The majority that had been diagnosed did not receive care as recommended by national guidelines and were not reported to the communicable diseases register responsible for hepatitis B virus surveillance. Future efforts should focus on linking individuals diagnosed with chronic hepatitis B virus infection to specialised care and improving reporting to the hepatitis B virus surveillance system.

Item Type: Article
Additional Information: This is an Accepted Manuscript of an article published by Taylor & Francis in on 11/10/2022, available at: http://www.tandfonline.com/10.1080/23744235.2022.2125065
Uncontrolled Keywords: Denmark; Prevalence; capture-recapture; chronic hepatitis B virus infection
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Public Health Institute
Publisher: Taylor & Francis
SWORD Depositor: A Symplectic
Date Deposited: 07 Dec 2022 13:04
Last Modified: 11 Oct 2023 00:50
DOI or ID number: 10.1080/23744235.2022.2125065
URI: https://researchonline.ljmu.ac.uk/id/eprint/17918
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