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Rosala-Hallas, A, Jones, AP, Williamson, PR, Bedson, E, Compton, V, Fernandes, RM, Lacy, D, Lyttle, MD, Peak, M, Thorburn, K, Woolfall, K, Van Miert, C and McNamara, PS (2022) Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop. BMJ Open, 12 (3). ISSN 2044-6055
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Which outcomes should be used in future bronchiolitis trials Developing a bronchiolitis core outcome set using a systematic review.pdf - Published Version Available under License Creative Commons Attribution Non-commercial. Download (318kB) | Preview |
Abstract
Objectives The objective of this study was to develop a core outcome set (COS) for use in future clinical trials in bronchiolitis. We wanted to find out which outcomes are important to healthcare professionals (HCPs) and to parents and which outcomes should be prioritised for use in future clinical trials.
Design and setting The study used a systematic review, workshops and interviews, a Delphi survey and a final consensus workshop.
Results Thirteen parents and 45 HCPs took part in 5 workshops; 15 other parents were also separately interviewed. Fifty-six items were identified from the systematic review, workshops and interviews. Rounds one and two of the Delphi survey involved 299 and 194 participants, respectively. Sixteen outcomes met the criteria for inclusion within the COS. The consensus meeting was attended by 10 participants, with representation from all three stakeholder groups. Nine outcomes were added, totalling 25 outcomes to be included in the COS.
Conclusion We have developed the first parent and HCP consensus on a COS for bronchiolitis in a hospital setting. The use of this COS will ensure outcomes in future bronchiolitis trials are important and relevant, and will enable the trial results to be compared and combined.
| Item Type: | Article |
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| Uncontrolled Keywords: | bronchiolitis; CHILDREN; core outcome sets; General & Internal Medicine; Life Sciences & Biomedicine; Medicine, General & Internal; OXYGEN; paediatrics; RANDOMIZED-TRIALS; Science & Technology; Science & Technology; Life Sciences & Biomedicine; Medicine, General & Internal; General & Internal Medicine; core outcome sets; bronchiolitis; paediatrics; RANDOMIZED-TRIALS; CHILDREN; OXYGEN; Humans; Bronchiolitis; Treatment Outcome; Consensus; Research Design; Delphi Technique; Outcome Assessment, Health Care; bronchiolitis; core outcome sets; paediatrics; Bronchiolitis; Consensus; Delphi Technique; Humans; Outcome Assessment, Health Care; Research Design; Treatment Outcome; 1103 Clinical Sciences; 1117 Public Health and Health Services; 1199 Other Medical and Health Sciences |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services |
| Divisions: | Nursing & Allied Health |
| Publisher: | BMJ Publishing Group |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 26 Jan 2023 11:55 |
| Last Modified: | 26 Jan 2023 12:00 |
| DOI or ID number: | 10.1136/bmjopen-2021-052943 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/18740 |
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