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Mantle, D and Hargreaves, IP (2023) Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel), 12 (2). ISSN 2076-3921
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Abstract
Mitochondrial dysfunction and oxidative stress have been implicated in the pathogenesis of a number of endocrine disorders; this, in turn, suggests a potential role for the vitamin-like substance coenzyme Q10 (CoQ10) in the pathogenesis and treatment of these disorders, on the basis of its key roles in mitochondrial function, and as an antioxidant. In this article we have therefore reviewed the role of CoQ10 deficiency and supplementation in disorders of the thyroid, pancreas, gonads, pituitary and adrenals, with a particular focus on hyperthyroidism, type II diabetes, male infertility and polycystic ovary syndrome.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | coenzyme Q10; diabetes; hyperthyroidism; male infertility; polycystic ovary syndrome |
| Subjects: | Q Science > QH Natural history > QH301 Biology R Medicine > RC Internal medicine R Medicine > RS Pharmacy and materia medica |
| Divisions: | Pharmacy & Biomolecular Sciences |
| Publisher: | MDPI AG |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 06 Mar 2023 12:05 |
| Last Modified: | 06 Mar 2023 12:05 |
| DOI or ID number: | 10.3390/antiox12020514 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/19032 |
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