Lee, J, Tang, J, Dutton, J, Dunn, R, Fraser, WD, Enright, KJ, Clark, DR, Stewart, CE and Erskine, R (2023) The Collagen Synthesis Response to an Acute Bout of Resistance Exercise Is Greater when Ingesting 30 g Hydrolyzed Collagen Compared with 15 g and 0 g in Resistance-Trained Young Men. The Journal of Nutrition. ISSN 0022-3166

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Text The collagen synthesis response to an acute bout of resistance exercise is greater when ingesting 30 g versus 15 g and 0 g hydrolyzed collagen in resistance trained young men.pdf - Published Version Available under License Creative Commons Attribution. Download (1MB) | Preview

Abstract

Background Resistance exercise (RE) stimulates collagen synthesis in skeletal muscle and tendon but there is limited and equivocal evidence regarding an effect of collagen supplementation and exercise on collagen synthesis. Furthermore, it is not known if a dose–response exists regarding the effect of hydrolyzed collagen (HC) ingestion and RE on collagen synthesis. Objective To determine the HC dose–response effect on collagen synthesis after high-intensity RE in resistance-trained young men. Methods Using a double-blind, randomized crossover design, 10 resistance-trained males (age: 26 ± 3 y; height: 1.77 ± 0.04 m; mass: 79.7 ± 7.0 kg) ingested 0 g, 15 g, or 30 g HC with 50 mg vitamin C 1 h before performing 4 sets’ barbell back squat RE at 10-repetition maximum load, after which they rested for 6 h. Blood samples were collected throughout each of the 3 interventions to analyze procollagen type Ⅰ N-terminal propeptide (PINP) and β-isomerized C-terminal telopeptide of type I collagen (β-CTX) concentration, and the concentration of 18 collagen amino acids. Results The serum PINP concentration × time area under the curve (AUC) was greater for 30 g (267 ± 79 μg·L−1·h) than for 15 g (235 ± 70 μg·L−1·h, P = 0.013) and 0 g HC (219 ± 88 μg·L−1·h, P = 0.002) but there was no difference between 0 and 15 g HC (P = 0.225). The AUCs of glycine and proline were greater for 30 g than for 15 and 0 g HC (P < 0.05). Plasma β-CTX concentration decreased from −1 to +6 h (P < 0.05), with no differences between interventions. Conclusions Ingesting 30 g HC before high-intensity RE augments whole-body collagen synthesis more than 15 g and 0 g HC in resistance-trained young males.

Item Type:	Article
Uncontrolled Keywords:	0702 Animal Production; 0908 Food Sciences; 1111 Nutrition and Dietetics; Nutrition & Dietetics
Subjects:	T Technology > TX Home economics > TX341 Nutrition. Foods and food supply R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions:	Sport & Exercise Sciences
Publisher:	Elsevier
SWORD Depositor:	A Symplectic
Date Deposited:	27 Oct 2023 10:45
Last Modified:	26 Jan 2024 11:15
DOI or ID number:	10.1016/j.tjnut.2023.10.030
URI:	https://researchonline.ljmu.ac.uk/id/eprint/21753

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