A clinical approach to the investigation and management of long COVID associated neuropathic pain

Shil, RSK orcid iconORCID: 0000-0001-9100-6114, Hughes, TW orcid iconORCID: 0000-0002-1561-7615, Sargent, BF orcid iconORCID: 0000-0003-2262-7755, Huang, Y orcid iconORCID: 0000-0001-7843-9126, Tamborska, AA orcid iconORCID: 0000-0003-4661-8407, Frank, B orcid iconORCID: 0000-0001-5405-4942, Ellul, MA orcid iconORCID: 0000-0002-6115-8245 and Michael, BD orcid iconORCID: 0000-0002-8693-8926 (2023) A clinical approach to the investigation and management of long COVID associated neuropathic pain. European Archives of Psychiatry and Clinical Neuroscience. ISSN 0940-1334

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Abstract

COVID–19 has been associated with a wide range of ongoing symptoms following recovery from the acute SARS-CoV-2 infection. Around one in three people with COVID-19 develop neurological symptoms with many reporting neuropathic pain and associated symptoms, including paraesthesia, numbness, and dysesthesia. Whilst the pathophysiology of long COVID-19-associated neuropathic pain remains unclear, it is likely to be multifactorial. Early identification, exclusion of common alternative causes, and a biopsychosocial approach to the management of the symptoms can help in relieving the burden of disease and improving the quality of life for patients.

Item Type: Article
Uncontrolled Keywords: COVID-19; Long Covid; Neuropathy; Pain; Paraesthesia; 1103 Clinical Sciences; 1109 Neurosciences; 1702 Cognitive Sciences; Psychiatry
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Psychology (from Sep 2019)
Publisher: Springer
Date of acceptance: 4 November 2023
Date of first compliant Open Access: 12 March 2024
Date Deposited: 12 Mar 2024 13:15
Last Modified: 04 Jul 2025 13:30
DOI or ID number: 10.1007/s00406-023-01721-8
URI: https://researchonline.ljmu.ac.uk/id/eprint/22785
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