Cronin, MTD, Jaworska, JS, Walker, JD, Comber, MHI, Watts, CD and Worth, AP (2003) Use of QSARs in international decision-making frameworks to predict health effects of chemical substances. ENVIRONMENTAL HEALTH PERSPECTIVES, 111 (10). pp. 1391-1401. ISSN 0091-6765

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Abstract

This article is a review of the use of quantitative (and qualitative) structure-activity relationships (QSARs and SARs) by regulatory agencies and authorities to predict acute toxicity, mutagenicity, carcinogenicity, and other health effects. A number of SAR and QSAR applications, by regulatory agencies and authorities, are reviewed. These include the use of simple QSAR analyses, as well as the use of multivariate QSARs, and a number of different expert system approaches.

Item Type:	Article
Additional Information:	Reproduced with permission from Environmental Health Perspectives
Uncontrolled Keywords:	11 Medical And Health Sciences, 05 Environmental Sciences
Subjects:	R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica
Divisions:	Pharmacy & Biomolecular Sciences
Publisher:	US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE
Related URLs:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000184746600043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=7f77ca1697db64ccb27a8011c7ced90d
Date Deposited:	02 Feb 2016 15:21
Last Modified:	04 Sep 2021 13:50
DOI or ID number:	10.1289/ehp.5760
URI:	https://researchonline.ljmu.ac.uk/id/eprint/2304

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