Cronin, MTD, Walker, JD, Jaworska, JS, Comber, MHI, Watts, CD and Worth, AP (2003) Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. ENVIRONMENTAL HEALTH PERSPECTIVES, 111 (10). pp. 1376-1390. ISSN 0091-6765

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Abstract

This article is a review of the use, by regulatory agencies and authorities, of quantitative structure–activity relationships (QSARs) to predict ecologic effects and environmental fate of chemicals. For many years, the U.S. Environmental Protection Agency has been the most prominent regulatory agency using QSARs to predict the ecologic effects and environmental fate of chemicals. However, as increasing numbers of standard QSAR methods are developed and validated to predict ecologic effects and environmental fate of chemicals, it is anticipated that more regulatory agencies and authorities will find them to be acceptable alternatives to chemical testing.

Item Type:	Article
Additional Information:	Reproduced with permission from Environmental Health Perspectives
Uncontrolled Keywords:	11 Medical And Health Sciences, 05 Environmental Sciences
Subjects:	R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica
Divisions:	Pharmacy & Biomolecular Sciences
Publisher:	US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE
Related URLs:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000184746600042&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=7f77ca1697db64ccb27a8011c7ced90d
Date Deposited:	03 Feb 2016 09:24
Last Modified:	20 Apr 2022 09:01
DOI or ID number:	10.1289/ehp.5759
URI:	https://researchonline.ljmu.ac.uk/id/eprint/2305

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