Yang, Y, Thackray, AE, Shen, T, Alotaibi, TF, Alanazi, TM, Clifford, T, Hartescu, I, King, JA, Roberts, MJ, Willis, SA, Lolli, L, Atkinson, G and Stensel, DJ A replicate crossover trial on the inter-individual variability of sleep indices in response to acute exercise undertaken by healthy men. Sleep. ISSN 0161-8105 (Accepted)

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Abstract

Study objective: Using the necessary replicate-crossover design, we investigated whether there is inter-individual variability in home-assessed sleep in response to acute exercise. Methods: Eighteen healthy men (mean(SD): 26(6) years) completed two identical control (8-h laboratory rest, 08:45-16:45) and two identical exercise (7-h laboratory rest; 1-h laboratory treadmill run [62(7)% peak oxygen uptake], 15:15-16:15) trials in randomised sequences. Wrist-worn actigraphy (MotionWatch 8) measured home-based sleep (total sleep time, actual wake time, sleep latency, sleep efficiency) two nights before (nights 1-2) and three nights after (nights 3-5) the exercise/control day. Pearson’s correlation coefficients quantified the consistency of individual differences between the replicates of control-adjusted exercise responses to explore: (1) immediate (night 3 minus night 2); (2) delayed (night 5 minus night 2); and (3) overall (average post-intervention minus average pre-intervention) exercise-related effects. Within-participant linear mixed models and a random-effects between-participant meta-analysis estimated participant-by-trial response heterogeneity. Results: For all comparisons and sleep outcomes, the between-replicate correlations were non-significant, ranging from trivial-to-moderate (r range = -0.44 to 0.41, P≥0.065). Participant-by-trial interactions were trivial. Individual differences SDs were small, prone to uncertainty around the estimates indicated by wide 95% confidence intervals and did not provide support for true individual response heterogeneity. Meta-analyses of the between-participant, replicate-averaged condition effect revealed that, again, heterogeneity (τ) was negligible for most sleep outcomes. Conclusion: Control-adjusted sleep in response to acute exercise was inconsistent when measured on repeated occasions. Inter-individual differences in sleep in response to exercise were small compared to the natural (trial-to-trial) within-subject variability in sleep outcomes.

Item Type:	Article
Uncontrolled Keywords:	06 Biological Sciences; 11 Medical and Health Sciences; 17 Psychology and Cognitive Sciences; Neurology & Neurosurgery
Subjects:	R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions:	Sport and Exercise Sciences
Publisher:	Oxford University Press
SWORD Depositor:	A Symplectic
Date Deposited:	17 Oct 2024 08:57
Last Modified:	17 Oct 2024 09:00
URI:	https://researchonline.ljmu.ac.uk/id/eprint/24539

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