Summers, JJ, Kang, N and Cauraugh, JH (2015) Does transcranial direct current stimulation enhance cognitive and motor functions in the ageing brain? A systematic review and meta- analysis. Ageing Research Reviews, 25. pp. 42-54. ISSN 1568-1637

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Abstract

The use of transcranial direct current stimulation (tDCS) to enhance cognitive and motor functions has enjoyed a massive increase in popularity. Modifying neuroplasticity via non-invasive cortical stimulation has enormous potential to slow or even reverse declines in functions associated with ageing. The current meta-analysis evaluated the effects of tDCS on cognitive and motor performance in healthy older adults. Of the 81 studies identified, 25 qualified for inclusion. A random effects model meta-analysis revealed a significant overall standardized mean difference equal to 0.53 (SE = 0.09; medium heterogeneity: I = 57.08%; and high fail-safe: N = 448). Five analyses on moderator variables indicated significant tDCS beneficial effects: (a) on both cognitive and motor task performances, (b) across a wide-range of cognitive tasks, (c) on specific brain areas, (d) stimulation offline (before) or online (during) the cognitive and motor tasks. Although the meta-analysis revealed robust support for enhancing both cognitive and motor performance, we outline a number of caveats on the use of tDCS.

Item Type:	Article
Uncontrolled Keywords:	0601 Biochemistry And Cell Biology, 1103 Clinical Sciences
Subjects:	R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions:	Sport & Exercise Sciences
Publisher:	Elsevier
Date Deposited:	17 Dec 2015 07:55
Last Modified:	04 Sep 2021 13:43
DOI or ID number:	10.1016/j.arr.2015.11.004
URI:	https://researchonline.ljmu.ac.uk/id/eprint/2486

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