Cronin, MTD, Berggren, E, Camorani, S, Desaintes, C, Fabbri, M, Fabrega, J, Herzler, M, Ingram, JDE, Lacasse, K, Maxwell, G, Schutte, K, Sobanski, T, Streck, G, Terron, A and Worth, AP (2025) Report of the European Commission Workshop on “The Roadmap Towards Phasing Out Animal Testing for Chemical Safety Assessments”, Brussels, 11-12 December 2023. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

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Abstract

This report summarises the main findings and discussion from the European Commission (EC) workshop on “The Roadmap Towards Phasing Out Animal Testing for Chemical Safety Assessments” which was held in Brussels on 11-12 December, 2023. The aim of the workshop was to gather ideas and opinions from individuals, organisations and institutions, and to discuss potential approaches for incorporating non-animal methods into chemical legislation with all interested stakeholders. The roadmap will be an EC policy document which will outline milestones and specific actions, addressing all relevant pieces of chemical legislation relating to safety assessment. It intends to describe the necessary steps to replace animal testing in pieces of legislation where it is currently required for chemical safety assessments. The roadmap will outline the path to expand and accelerate the development, validation and implementation of non-animal methods as well as means to facilitate their uptake across legislation. The workshop included presentations and discussion from a wide variety of stakeholders. The contributors provided examples of how non-animal methods could be applied to replace, reduce or refine animal testing in the assessment of human health and environmental effects. Furthermore, possible guiding principles for establishing a Next-Generation Risk Assessment (NGRA) in European chemicals legislation were also discussed. The workshop provided the basis for further discussion and for structuring further roadmap work.

Item Type:	Article
Uncontrolled Keywords:	1115 Pharmacology and Pharmaceutical Sciences; Toxicology; 3214 Pharmacology and pharmaceutical sciences
Subjects:	Q Science > QD Chemistry R Medicine > RS Pharmacy and materia medica
Divisions:	Pharmacy and Biomolecular Sciences
Publisher:	Elsevier
SWORD Depositor:	A Symplectic
Date Deposited:	07 Apr 2025 09:46
Last Modified:	07 Apr 2025 09:46
DOI or ID number:	10.1016/j.yrtph.2025.105818
URI:	https://researchonline.ljmu.ac.uk/id/eprint/26102

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