Singh, PB (2016) Heterochromatin and the molecular mechanisms of ‘parent-of-origin’ effects in animals. Journal of Biosciences, 41 (4). pp. 759-786. ISSN 0250-5991
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Abstract
Twenty five years ago it was proposed that conserved components of constitutive heterochromatin assemble heterochromatin-like complexes in euchromatin and this could provide a general mechanism for regulating heritable (cell-to-cell) changes in gene expressibility. As a special case, differences in the assembly of heterochromatin-like complexes on homologous chromosomes might also regulate the parent-of-origin-dependent gene expression observed in placental mammals. Here, the progress made in the intervening period with emphasis on the role of heterochromatin and heterochromatin-like complexes in parent-of-origin effects in animals is reviewed.
Item Type: | Article |
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Additional Information: | © 2016 Indian Academy of Sciences |
Uncontrolled Keywords: | 06 Biological Sciences |
Subjects: | Q Science > QH Natural history Q Science > QH Natural history > QH301 Biology Q Science > QL Zoology |
Divisions: | Natural Sciences & Psychology (closed 31 Aug 19) |
Publisher: | Indian Academy of Sciences |
Date Deposited: | 22 Dec 2016 14:48 |
Last Modified: | 20 Apr 2022 09:31 |
DOI or ID number: | 10.1007/s12038-016-9650-9 |
URI: | https://researchonline.ljmu.ac.uk/id/eprint/5155 |
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