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Lactones and Flavonoids isolated from the Leaves of Globimetula braunii

Ja'afar, MK, Jamil, S, Basar, N, Bakar, MB, Sarker, SD, Flanagan, KJ and Senge, MO (2017) Lactones and Flavonoids isolated from the Leaves of Globimetula braunii. Natural Product Communications, 12 (9). pp. 1455-1458. ISSN 1934-578X

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Abstract

The dried powdered leaves of Globimetula braunii (Engler) Van Tiegh were effectively extracted by the cold extraction method. Purification of the EtOAc-soluble and MeOH-soluble extracts successfully yielded two lactones namely (R)-6-[(S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]–5,6-dihydropyran-2-one (dodoneine) 1 and (1R,5S,7S)-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]-nonan-3-one (2), together with five flavonoids namely quercetin 3, (+)-catechin 4, quercitrin 5, rutin 6 and avicularin 7. Their structures were established by spectroscopic means, and the absolute configuration of compound 1 was confirmed by X-ray analysis.

Item Type: Article
Uncontrolled Keywords: 0305 Organic Chemistry, 0607 Plant Biology
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Pharmacy & Biomolecular Sciences
Publisher: SAGE Publications
Related URLs:
Date Deposited: 07 Jan 2020 09:58
Last Modified: 07 Jan 2020 10:00
DOI or Identification number: 10.1177/1934578X1701200918
URI: http://researchonline.ljmu.ac.uk/id/eprint/7563

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