Li, X-Q, Song, Y-N, Wang, S-J, Rahman, K, Zhu, J-Y and Zhang, H (2018) Saikosaponins: a review of pharmacological effects. Journal of Asian Natural Products Research. ISSN 1028-6020

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Abstract

Over the past decades, a number of phytochemicals have been reported to possess potent pharmacological effects. Saikosaponins represent a group of oleanane derivatives, usually as glucosides, which are commonly found in medicinal plants Bupleurum spp., which have been used as traditional Chinese medicine for more than 1,000 years in China. Emerging evidence suggests that saikosaponins have many pharmacological effects, including sedation, anticonvulsant, antipyretic, antiviral, immunity, anti-inflammation, antitumor properties, protecting liver and kidney and so on. The present review provides a comprehensive summary and analysis of the pharmacological properties of saikosaponins, supporting the potential uses of saikosaponins as a medicinal agent.

Item Type:	Article
Additional Information:	This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Asian Natural Products Research on 04/05/2018, available online: http://www.tandfonline.com/10.1080/10286020.2018.1465937
Uncontrolled Keywords:	0305 Organic Chemistry, 0607 Plant Biology, 1115 Pharmacology And Pharmaceutical Sciences
Subjects:	R Medicine > RM Therapeutics. Pharmacology
Divisions:	Pharmacy & Biomolecular Sciences
Publisher:	Taylor & Francis
Related URLs:	https://www.ncbi.nlm.nih.gov/pubmed/29726699
Date Deposited:	15 May 2018 10:30
Last Modified:	04 Sep 2021 10:30
DOI or ID number:	10.1080/10286020.2018.1465937
URI:	https://researchonline.ljmu.ac.uk/id/eprint/8667

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