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Al-Majmaie, S, Nahar, L, Sharples, GP, Wadi, K and Sarker, SD (2019) Isolation and antimicrobial activity of rutin and its derivatives from Ruta chalepensis (Rutaceae) growing in Iraq. Records of Natural Products, 13 (1). pp. 64-70. ISSN 1307-6167
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Isolation and antimicrobial activity of rutin and its derivatives from Ruta chalepensis (Rutaceae) growing in Iraq.pdf - Accepted Version Download (582kB) | Preview |
Abstract
Rutin (1), rutin 3'-methyl ether (2), and a new flavonol glycoside, 6-hydroxy-rutin 3',7-dimethyl ether (3), were isolated from the methanol extract of the fruits of Ruta chalepensis, collected from Diyala, Iraq. Their structures were elucidated by spectroscopic analyses, including 1D-, 2D-NMR and HRESIMS. Antimicrobial activity of compounds 1-3 was tested against four Gram +ve and Gram –ve bacterial strains, and the only fungal strain, Candida albicans, using the 96-well based resazurin microtitre assay.
| Item Type: | Article |
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| Subjects: | Q Science > QD Chemistry Q Science > QR Microbiology R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Pharmacy & Biomolecular Sciences |
| Publisher: | ACG Publications |
| Date Deposited: | 22 May 2018 09:36 |
| Last Modified: | 04 Sep 2021 10:29 |
| DOI or ID number: | 10.25135/rnp.74.18.03.250 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/8691 |
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