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Guetchueng, S, Nahar, L, Ritchie, KJ, Ismail, FMD, Evans, AR and Sarker, SD (2018) Zanthoamides G-I: Three new alkamides from Zanthoxylum zanthoxyloides. Phytochemistry Letters, 26. pp. 125-129. ISSN 1874-3900
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Zanthoamides G-I Three new alkamides from Zanthoxylum zanthoxyloides.pdf - Accepted Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (737kB) | Preview |
Abstract
Three new alkamides, zanthoamides G-I (1-3), together with ten known compounds, araliopsine, skimmianine, N-methylplatydesminium cation, isoplatydesmine, myrtopsine, atanine, N-methylatanine, sesamin, hesperetin and hesperidin, were isolated from the fruits of Zanthoxylum zanthoxyloides. Their structures were elucidated by spectroscopic means. All isolated compounds were assessed for their cytotoxicity against A549, MCF7, PC3 and PNT2 cell lines. Among the alkamides, only zanthoamide G (1) showed low level of cytotoxicity against MCF7 cells.
| Item Type: | Article |
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| Uncontrolled Keywords: | 0304 Medicinal And Biomolecular Chemistry, 0607 Plant Biology, 1115 Pharmacology And Pharmaceutical Sciences |
| Subjects: | Q Science > QD Chemistry R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Pharmacy & Biomolecular Sciences |
| Publisher: | Elsevier |
| Date Deposited: | 23 May 2018 08:38 |
| Last Modified: | 04 Sep 2021 10:28 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/8699 |
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