Article

Thompson, CV, Webb, SD, Leedale, JA, Penson, PE, Paini, A, Ebbrell, DJ and Madden, JC (2023) Using Read-Across to Build Physiologically-Based Kinetic Models: Part 2. Case Studies for atenolol and flumioxazin. Computational Toxicology, 29. p. 100293. ISSN 2468-1113

Firman, JW, Ebbrell, DJ, Bauer, FJ, Sapounidou, M, Hodges, G, Campos, B, Roberts, J, Gutsell, S, Thomas, PC, Bonnell, M and Cronin, MTD (2022) Construction of an In Silico Structural Profiling Tool Facilitating Mechanistically Grounded Classification of Aquatic Toxicants. Environmental Science and Technology. ISSN 0013-936X

Cronin, MTD, Bauer, FJ, Bonnell, M, Campos, B, Ebbrell, DJ, Firman, JW, Gutsell, S, Hodges, G, Patlewicz, G, Sapounidou, M, Spinu, N, Thomas, PC and Worth, AP (2022) A scheme to evaluate structural alerts to predict toxicity – Assessing confidence by characterising uncertainties. Regulatory Toxicology and Pharmacology, 135. ISSN 0273-2300

Arnesdotter, E, Spinu, N, Firman, JW, Ebbrell, DJ, Cronin, MTD, Vanhaecke, T and Vinken, M (2021) Derivation, characterisation and analysis of an adverse outcome pathway network for human hepatotoxicity. Toxicology. ISSN 0300-483X

Paini, A, Worth, A, Kulkarni, S, Ebbrell, DJ and Madden, JC (2021) Assessment of the predictive capacity of a physiologically based kinetic model using a read-across approach. Computational Toxicology, 18. ISSN 2468-1113

Sapounidou, M, Ebbrell, DJ, Bonnell, M, Campos, B, Firman, J, Gitsell, S and Cronin, MTD (2021) Development of an Enhanced Mechanistically-Driven Mode of Action Classification Scheme for Adverse Effects in Environmental Species. Environmental Science and Technology, 55 (3). pp. 1897-1907. ISSN 0013-936X

Ebbrell, DJ, Madden, JC, Cronin, MTD, Schultz, T and Enoch, SJ (2019) Development of a fragment-based in silico profiler for SN2 thiol reactivity and its application in predicting toxicity of chemicals towards Tetrahymena pyriformis. Computational Toxicology, 13. ISSN 2468-1113

Pawar, G, Madden, JC, Ebbrell, DJ, Firman, JW and Cronin, MTD (2019) In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR. Frontiers in Pharmacology, 10. ISSN 1663-9812

Mellor, CL, Marchese Robinson, RL, Benigni, R, Ebbrell, DJ, Enoch, SJ, Firman, JW, Madden, JC, Pawar, G, Yang, C and Cronin, MTD (2018) Molecular Fingerprint-Derived Similarity Measures for Toxicological Read-Across: Recommendations for Optimal Use. Regulatory Toxicology and Pharmacology, 101. pp. 121-134. ISSN 0273-2300

Ebbrell, DJ, Madden, JC, Cronin, MTD, Schultz, TW and Enoch, SJ (2017) Validation of a fragment-based profiler for thiol reactivity for the prediction of toxicity: skin sensitisation and tetrahymena pyriformis. Chemical Research in Toxicology, 30 (2). pp. 604-613. ISSN 0893-228X

Ebbrell, DJ, Madden, JC, Cronin, MTD, Schultz, TW and Enoch, SJ (2016) Development of a Fragment-Based in Silico Profiler for Michael Addition Thiol Reactivity. Chemical Research in Toxicology, 29 (6). pp. 1073-1081. ISSN 1520-5010

Thesis

Ebbrell, DJ (2018) The Development of a Fragment-Based in silico Profiler for the Prediction of Thiol Reactivity and Toxicity. Doctoral thesis, Liverpool John Moores University.