Items where Author is "Heales, S"
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Gurung, S, Timmermand, OV, Perocheau, D, Gil-Martinez, AL, Minnion, M, Touramanidou, L, Fang, S, Messina, M, Khalil, Y, Spiewak, J, Barber, AR, Edwards, RS, Pinto, PL, Finn, PF, Cavedon, A, Siddiqui, S, Rice, L, Martini, PGV, Ridout, D, Heywood, W , Hargreaves, I, Heales, S, Mills, PB, Waddington, SN, Gissen, P, Eaton, S, Ryten, M, Feelisch, M, Frassetto, A, Witney, TH and Baruteau, J (2024) mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science Translational Medicine, 16 (729). ISSN 1946-6234
Toomey, CE, Heywood, WE, Evans, JR, Lachica, J, Pressey, SN, Foti, SC, Al Shahrani, M, D’Sa, K, Hargreaves, IP, Heales, S, Orford, M, Troakes, C, Attems, J, Gelpi, E, Palkovits, M, Lashley, T, Gentleman, SM, Revesz, T, Mills, K and Gandhi, S (2022) Mitochondrial dysfunction is a key pathological driver of early stage Parkinson’s. Acta Neuropathologica ommunications, 10. pp. 1-25.
Heaton, R, Heales, S, Rahman, K, Sexton, DW and Hargreaves, IP (2020) The Effect of Cellular Coenzyme Q10 Deficiency on Lysosomal Acidification. Journal of Clinical Medicine, 9 (6). ISSN 2077-0383
Ng, X, Sadeghian, M, Heales, S and Hargreaves, IP (2019) Assessment of Mitochondrial Dysfunction in Experimental Autoimmune Encephalomyelitis (EAE) Models of Multiple Sclerosis. International Journal of Molecular Sciences, 20 (20). ISSN 1661-6596
Hargreaves, IP, Mody, N, Land, J and Heales, S (2018) Blood Mononuclear Cell Mitochondrial Respiratory Chain Complex IV Activity is Decreased in Multiple Sclerosis Patients: Effects of beta-Interferon Treatment. Journal of Clinical Medicine, 7 (2). ISSN 2077-0383
Al Shahrani, M, Heales, S, Hargreaves, IP and Orford, M (2017) Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson's Disease. Journal of Clinical Medicine, 6 (11). ISSN 2077-0383
Manole, A, Jaunmuktane, Z, Hargreaves, IP, Ludtmann, MHR, Salpietro, V, Bello, OD, Pope, S, Pandraud, A, Horga, A, Scalco, RS, Li, A, Ashokkumar, B, Lourenco, CM, Heales, S, Horvath, R, Chinnery, PF, Toro, C, Singleton, AB, Jacques, TS, Abramov, AY , Muntoni, F, Hanna, MG, Reilly, MM, Revesz, T, Kullmann, DM, Jepson, JEC and Houlden, H (2017) Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. Brain, 140 (11). pp. 2820-2837. ISSN 1460-2156
Sadeghian, M, Mastrolia, V, Rezaei Haddad, A, Mosley, A, Mullali, G, Schiza, D, Sajic, M, Hargreaves, IP, Heales, S, Duchen, MR and Smith, KJ (2016) Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis. Scientific Reports, 6 (1). ISSN 2045-2322
Wood-Kaczmar, A, Gandhi, S, Yao, Z, Abramov, ASY, Miljan, EA, Keen, G, Stanyer, L, Hargreaves, IP, Klupsch, K, Deas, E, Downward, J, Mansfield, L, Jat, P, Taylor, J, Heales, S, Duchen, MR, Latchman, D, Tabrizi, SJ and Wood, NW (2008) PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons. PLoS One, 3 (6). ISSN 1932-6203