Items where Author is "Spinu, N"
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Cronin, M, Basiri, H, Chrysochoou, G, Enoch, SJ, Firman, JW, Spinu, N and Madden, JC (2024) The predictivity of QSARs for toxicity: Recommendations for improving model performance. Computational Toxicology, 33.
Cronin, MTD, Bauer, FJ, Bonnell, M, Campos, B, Ebbrell, DJ, Firman, JW, Gutsell, S, Hodges, G, Patlewicz, G, Sapounidou, M, Spinu, N, Thomas, PC and Worth, AP (2022) A scheme to evaluate structural alerts to predict toxicity – Assessing confidence by characterising uncertainties. Regulatory Toxicology and Pharmacology, 135. ISSN 0273-2300
Gadaleta, D, Spinu, N, Roncaglioni, A, Cronin, MTD and Benfenati, E (2022) Prediction Of The Neurotoxic Potential Of Chemicals Based On Modelling Of Molecular Initiating Events Upstream Of The Adverse Outcome Pathways Of (Developmental) Neurotoxicity. International Journal of Molecular Sciences, 23. ISSN 1422-0067
Pestana, C, Enoch, SJ, Firman, JW, Madden, JC, Spinu, N and Cronin, MTD (2022) A Strategy to Define Applicability Domains for Read-Across. Computational Toxicology, 22. ISSN 2468-1113
Spinu, N, Cronin, MTD, Lao, J, Bal-Price, A, Campia, I, Enoch, SJ, Madden, JC, Lagares, LM, Novič, M, Pamies, D, Scholz, S, Villeneuve, DL and Worth, A (2021) Probabilistic Modelling of Developmental Neurotoxicity based on a Simplified Adverse Outcome Pathway Network. Computational Toxicology, 21. ISSN 2468-1113
Spinu, N, Cronin, MTD, Madden, JC and Worth, A (2021) A Matter of Trust: Learning Lessons About Causality Will Make qAOPs Credible. Computational Toxicology, 21. ISSN 2468-1113
Paini, A, Campia, I, Cronin, M, Pletz, J and Spinu, N (2021) Towards a qAOP Framework for Predictive Toxicology - Linking Data to Decisions. Computational Toxicology, 21. ISSN 2468-1113
Arnesdotter, E, Spinu, N, Firman, JW, Ebbrell, DJ, Cronin, MTD, Vanhaecke, T and Vinken, M (2021) Derivation, characterisation and analysis of an adverse outcome pathway network for human hepatotoxicity. Toxicology. ISSN 0300-483X
Spinu, N (2021) Modelling of quantitative Adverse Outcome Pathways. Doctoral thesis, Liverpool John Moores University.
Spinu, N, Cronin, MTD, Enoch, SJ, Madden, JC and Worth, A (2020) Quantitative Adverse Outcome Pathway (qAOP) models for toxicity prediction. Archives of Toxicology, 94. pp. 1497-1510. ISSN 0340-5761
Spinu, N, Bal-Price, A, Cronin, MTD, Enoch, SJ, Madden, JC and Worth, A (2019) Development and Analysis of an Adverse Outcome Pathway Network for Human Neurotoxicity. Archives of Toxicology, 93 (10). pp. 2759-2772. ISSN 0340-5761