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Tryfonos, A, Green, DJ and Dawson, EA (2019) Effects of Catheterization on Artery Function and Health: When Should Patients Start Exercising Following Their Coronary Intervention? Sports Medicine. ISSN 0112-1642
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Effects of catheterization on artery function and health.pdf - Accepted Version Download (1MB) | Preview |
Abstract
Coronary artery disease (CAD) is a leading cause of death worldwide, and percutaneous transluminal coronary angiography (PTCA) and/or percutaneous coronary intervention (PCI; angioplasty) are commonly used to diagnose and/or treat the obstructed coronaries. Exercise-based rehabilitation is recommended for all CAD patients; however, most guidelines do not specify when exercise training should commence following PTCA and/or PCI. Catheterization can result in arterial dysfunction and acute injury, and given the fact that exercise, particularly at higher intensities, is associated with elevated inflammatory and oxidative stress, endothelial dysfunction and a pro-thrombotic milieu, performing exercise post-PTCA/PCI may transiently elevate the risk of cardiac events. This review aims to summarize extant literature relating to the impacts of coronary interventions on arterial function, including the time-course of recovery and the potential deleterious and/or beneficial impacts of acute versus long-term exercise. The current literature suggests that arterial dysfunction induced by catheterization recovers 4-12 weeks following catheterization. This review proposes that a period of relative arterial vulnerability may exist and exercise during this period may contribute to elevated event susceptibility. We therefore suggest that CAD patients start an exercise training programme between 2 and 4 weeks post-PCI, recognizing that the literature suggest there is a 'grey area' for functional recovery between 2 and 12 weeks post-catheterization. The timing of exercise onset should take into consideration the individual characteristics of patients (age, severity of disease, comorbidities) and the intensity, frequency and duration of the exercise prescription.
| Item Type: | Article |
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| Additional Information: | This is a post-peer-review, pre-copyedit version of an article published in Sports Medicine. The final authenticated version is available online at: http://dx.doi.org/10.1007/s40279-019-01055-3 |
| Uncontrolled Keywords: | 1106 Human Movement and Sports Sciences, 0913 Mechanical Engineering, 1302 Curriculum and Pedagogy |
| Subjects: | R Medicine > RC Internal medicine > RC1200 Sports Medicine |
| Divisions: | Sport & Exercise Sciences |
| Publisher: | Springer Verlag |
| Related URLs: | |
| Date Deposited: | 22 Feb 2019 09:39 |
| Last Modified: | 04 Sep 2021 09:42 |
| DOI or ID number: | 10.1007/s40279-019-01055-3 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/10198 |
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