Tools
Tools
Ezuruike, U and Prieto, JM (2016) Assessment of Potential Herb-Drug Interactions among Nigerian Adults with Type-2 Diabetes. Frontiers in Pharmacology, 7. ISSN 1663-9812
|
Text
Assessment of Potential Herb-Drug Interactions among Nigerian Adults with Type-2 Diabetes.pdf - Published Version Available under License Creative Commons Attribution. Download (359kB) | Preview |
Abstract
It is becoming increasingly evident that patients with diabetes do not rely only on prescription drugs for their disease management. The use of herbal medicines is one of the self-management practices adopted by these patients, often without the knowledge of their healthcare practitioners. This study assessed the potential for pharmacokinetic herb-drug interactions (HDIs) amongst Nigerian adult diabetic patients. This was done through a literature analysis of the pharmacokinetic profile of their herbal medicines and prescription drugs, based on information obtained from 112 patients with type-2 diabetes attending two secondary health care facilities in Nigeria. Fifty percent of the informants used herbal medicines alongside their prescription drugs. Worryingly, 60% of the patients taking herbal medicines did not know their identity, thus increasing the risk of unidentified HDIs. By comparing the pharmacokinetic profile of eight identified herbs taken by the patients for the management of diabetes against those of the prescription drugs, several scenarios of potential HDIs were identified and their clinical relevance is discussed. The lack of clinical predictors points toward cultural factors as the influence for herb use, making it more difficult to identify these patients and in turn monitor potential HDIs. In identifying these possible interactions, we have highlighted the need for healthcare professionals to promote a proactive monitoring of patients' use of herbal medicines.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 1115 Pharmacology and Pharmaceutical Sciences |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology R Medicine > RV Botanic, Thomsonian, and eclectic medicine |
| Divisions: | Pharmacy & Biomolecular Sciences |
| Publisher: | Frontiers Media |
| Related URLs: | |
| Date Deposited: | 27 Apr 2020 08:21 |
| Last Modified: | 04 Sep 2021 07:23 |
| DOI or ID number: | 10.3389/fphar.2016.00248 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/12829 |
 |
View Item |