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The Entamoeba lysine and glutamic acid rich protein (KERP1) virulence factor gene is present in the genomes of Entamoeba nuttalli, Entamoeba dispar and Entamoeba moshkovskii

Weedall, GD (2020) The Entamoeba lysine and glutamic acid rich protein (KERP1) virulence factor gene is present in the genomes of Entamoeba nuttalli, Entamoeba dispar and Entamoeba moshkovskii. Molecular and Biochemical Parasitology, 238. ISSN 0166-6851

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The Entamoeba lysine and glutamic acid rich protein KERP1 virulence factor gene is present in the genomes of Entamoeba nuttalli, Entamoeba dispar and Entamoeba moshkovskii.pdf - Accepted Version

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Abstract

The lysine and glutamic acid rich protein KERP1 is a cell surface-expressed virulence factor in the human pathogen Entamoeba histolytica. It was originally suggested that the gene was absent from the related, avirulent human commensal Entamoeba dispar, an absence which would be relevant to the differential virulence of these species. Here, the gene is shown to be present in E. dispar, and its sequence is presented, as well as in a virulent parasite of macaques, Entamoeba nuttalli, and the primarily free living, opportunistically parasitic Entamoeba moshkovskii.

Item Type: Article
Uncontrolled Keywords: 06 Biological Sciences, 07 Agricultural and Veterinary Sciences, 11 Medical and Health Sciences
Subjects: G Geography. Anthropology. Recreation > GE Environmental Sciences
Q Science > QH Natural history > QH301 Biology
Divisions: Biological & Environmental Sciences (from Sep 19)
Publisher: Elsevier
Related URLs:
Date Deposited: 11 Dec 2020 11:02
Last Modified: 04 Sep 2021 06:17
DOI or ID number: 10.1016/j.molbiopara.2020.111293
URI: https://researchonline.ljmu.ac.uk/id/eprint/14123
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