DANMARKS TEKNISKE UNIVERSITET & INL - INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY (2022) Variable Size Aptamer Libraries. WO/2022/003116.

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Abstract

The present invention provides a method for obtaining an aptamer capable of binding to a target, comprising the steps of generating a library of candidate aptamers of various sizes, incubating the candidate aptamers with the target and selecting the candidate aptamers that bind to the target. The present invention also relates to a kit for selection of a DNA or RNA aptamer. Further, the present invention relates to a method of diagnosing or treating a disorder or disease by generating and selecting aptamers against a target that characterizes the disease or disorder. The present invention also relates to a method of detecting the presence or absence of a target in a sample. Furthermore, the present invention relates to aptamers or a library of aptamers.

Item Type:	Patent
Subjects:	R Medicine > RM Therapeutics. Pharmacology
Divisions:	Pharmacy & Biomolecular Sciences
Date Deposited:	23 Feb 2022 11:38
Last Modified:	23 Feb 2022 11:38
DOI or ID number:	WO/2022/003116
URI:	https://researchonline.ljmu.ac.uk/id/eprint/16402

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