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Fairclough, SH, Stamp, K and Dobbins, C (2022) Functional Connectivity Across Dorsal And Ventral Attention Networks In Response To Task Difficulty And Experimental Pain. Neuroscience Letters, 793. ISSN 0304-3940
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Abstract
The dorsal and ventral attention networks (DAN & VAN) provide a framework for studying attentional modulation of pain. It has been argued that cognitive demand distracts attention from painful stimuli via top-down reinforcement of task goals (DAN), whereas pain exerts an interruptive effect on cognitive performance via bottom-up pathways (VAN). The current study explores this explanatory framework by manipulating pain and task demand in combination with functional near-infrared spectroscopy (fNIRS) and Granger Causal Connectivity Analyses (GCCA). Twenty-one participants played a racing game at low and high difficulty levels with or without experimental pain (administered via a cold pressor test). Six channels of fNIRS were collected from bilateral frontal eye fields and intraparietal sulci (DAN), with right-lateralised channels at the inferior frontal gyrus and temporoparietal junction (VAN). Our first analysis revealed increased G-causality from bottom-up pathways (VAN) during the cold pressor test. However, an equivalent experience of experimental pain during gameplay increased G-causality in top-down (DAN) pathways, with the left intraparietal sulcus serving a hub of connectivity. High game difficulty increased G-causality via top-down pathways and implicated the right inferior frontal gyrus as an interhemispheric hub. Our results are discussed with reference to existing models of both networks and attentional modulation of pain.
| Item Type: | Article |
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| Uncontrolled Keywords: | 1109 Neurosciences; 1701 Psychology; 1702 Cognitive Sciences |
| Subjects: | B Philosophy. Psychology. Religion > BF Psychology Q Science > QA Mathematics > QA75 Electronic computers. Computer science R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Computer Science & Mathematics Psychology (from Sep 2019) |
| Publisher: | Elsevier |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 17 Nov 2022 10:26 |
| Last Modified: | 21 Mar 2023 13:31 |
| DOI or ID number: | 10.1016/j.neulet.2022.136967 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/18158 |
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