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The role of nutraceuticals in heart failure muscle wasting as a result of inflammatory activity. The International Lipid Expert Panel (ILEP) Position Paper.

Bielecka-Dabrowa, AM, Banach, M, Wittczak, A, Cicero, AFG, Kallel, A, Kubilius, R, Mikhailidis, DP, Sahebkar, A, Stoian, AP, Vinereanu, D, Penson, PE and Haehling, SV (2023) The role of nutraceuticals in heart failure muscle wasting as a result of inflammatory activity. The International Lipid Expert Panel (ILEP) Position Paper. Archives of Medical Science, 19 (4). pp. 841-864. ISSN 1734-1922

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Abstract

Muscle wasting is one of the main causes for exercise intolerance and ventilatory inefficiency in patients with heart failure and a strong predictor of frailty and reduced survival. The prevalence of sarcopenia is at least 20% in patients with heart failure. Patients with heart failure often have subclinical systemic inflammation, which may exert sustained effects on skeletal muscle. Besides exercise, nutrition should also be carefully evaluated, as an appropriate diet with selected nutraceuticals may be able to stimulate muscle anabolism and inhibit muscle catabolism. This review summarizes the epidemiological and clinical trial evidence supporting the recommendations for the use of nutraceuticals with anti-inflammatory properties in heart failure and provides an overview of the state of the evidence for nutraceutical supplementation to prevent and/or mitigate heart failure muscle wasting.

Item Type: Article
Uncontrolled Keywords: 1103 Clinical Sciences; General & Internal Medicine
Subjects: Q Science > QH Natural history > QH301 Biology
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: Pharmacy & Biomolecular Sciences
Publisher: Termedia Publishing
SWORD Depositor: A Symplectic
Date Deposited: 18 Jul 2023 10:57
Last Modified: 18 Jul 2023 11:00
DOI or ID number: 10.5114/aoms/167799
URI: https://researchonline.ljmu.ac.uk/id/eprint/20411
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